Published online Jan 27, 2024. doi: 10.4240/wjgs.v16.i1.124
Peer-review started: November 21, 2023
First decision: December 5, 2023
Revised: December 16, 2023
Accepted: December 28, 2023
Article in press: December 28, 2023
Published online: January 27, 2024
The incidence of colorectal cancer (CRC) is increasing annually. Laparoscopic radical resection of CRC is a minimally invasive procedure preferred in clinical practice.
To investigate the clinical effect of laparoscopic radical resection of CRC on the basis of propensity score matching (PSM).
The clinical data of 100 patients who received inpatient treatment for CRC at Changde Hospital, Xiangya School of Medicine, Central South University (The First People’s Hospital of Changde City) were analyzed retrospectively. The control group included patients who underwent open surgery (n = 43), and those who underwent laparoscopic surgery formed the observation group (n = 57). The baseline information of both groups was equipoised using 1 × 1 PSM. Differences in the perioperative parameters, inflammatory response, immune function, degree of pain, and physical status between the groups were analyzed.
Thirty patients from both groups were successfully matched. After PSM, baseline data showed no statistically significant differences between the groups: (1) Perioperative parameters: The observation group had a longer surgery time, less intra
Laparoscopic radical resection of CRC has significant benefits, such as reducing postoperative pain and postoperative inflammatory response, avoiding excessive immune inhibition, and contributing to postoperative recovery.
Core Tip: Clinical data from 100 patients who underwent radical resection for colorectal cancer were retrospectively analyzed to compare the clinical effects of open and laparoscopic surgeries in terms of perioperative parameters, inflammatory response, immune function, degree of pain, and physical status.