Type 2 diabetes is associated with a worse functional outcome of ischemic stroke

Table 1 Clinical characteristics of patients with type 2 diabetes mellitus and those without

	Patients with T2DM (n = 155)	Patients without T2DM (n = 327)	P
Age (yr)	78.3 ± 6.3	79.1 ± 6.9	NS
Males (%)	38.7	41.0	NS
Systolic blood pressure (mmHg)	150 ± 24	146 ± 25	NS
Diastolic blood pressure (mmHg)	81 ± 10	81 ± 14	NS
Hypertension (%)	88.4	78.6	0.013
Smoking (current/past, %)	12.9/22.6	11.6/20.5	NS
Package-years	17 ± 39	14 ± 33	NS
Atrial fibrillation (%)	38.7	34.6	NS
Alcohol consumption (units/wk)	0.7 ± 2.4	2.1 ± 11.7	0.045
Weight (kg)	77.0 ± 13.0	73.7 ± 13.8	0.04
Body mass index (kg/m2)	28.1 ± 5.2	27.2 ± 5.1	NS
Waist (cm)	110 ± 9	101 ± 13	< 0.001
Waist/hip	1.00 ± 0.06	0.97 ± 0.08	NS
Overweight/obese (%)	44.1/26.9	38.5/25.0	NS
Family history of cardiovascular disease (%)	14.8	15.0	NS
Coronary heart disease (%)	35.5	23.9	0.01
Previous ischemic stroke (%)	44.5	37.9	NS
Chronic kidney disease (%)	36.9	33.5	NS
Chronic heart failure (%)	26.5	16.5	0.015

T2DM: Type 2 diabetes mellitus; NS: Not significant.

Table 2 Laboratory characteristics of patients with type 2 diabetes mellitus and those without

	Patients with T2DM (n = 155)	Patients without T2DM (n = 327)	P
Glucose (mg/dL)	145 ± 64	99 ± 27	< 0.001
LDL-C (mg/dL)	103 ± 43	116 ± 38	0.007
HDL-C (mg/dL)	43 ± 14	48 ± 15	0.002
Triglycerides (mg/dL)	136 ± 63	112 ± 44	0.001
Uric acid (mg/dL)	5.8 ± 1.8	5.7 ± 1.9	NS
eGFR (mL/min per 1.73 m2)	67 ± 22	70 ± 23	NS

T2DM: Type 2 diabetes mellitus; NS: Not significant; LDL-C: Low-density lipoprotein cholesterol; HDL-C: High-density lipoprotein cholesterol; eGFR: Estimated glomerular filtration rate.

Table 3 Severity of stroke and outcome of patients with type 2 diabetes mellitus and those without

	Patients with T2DM (n = 155)	Patients without T2DM (n = 327)	P
National Institutes of Health Stroke Scale score at admission	8.7 ± 8.8	8.6 ± 9.2	NS
Duration of hospitalization (d)	6.9 ± 4.6	6.7 ± 4.1	NS
Modified Rankin scale score at discharge	2.7 ± 2.1	2.7 ± 2.2	NS
Adverse outcome (%)	62.3	58.5	NS
In-hospital mortality (%)	9	9.8	NS

T2DM: Type 2 diabetes mellitus; NS: Not significant.