Sirtuins as novel players in the pathogenesis of diabetes mellitus

doi:10.4239/wjd.v5.i6.894

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World Journal of Diabetes

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1948-9358

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Diabetes. Dec 15, 2014; 5(6): 894-900
Published online Dec 15, 2014. doi: 10.4239/wjd.v5.i6.894

Table 1 The characteristic features of sirtuins

Sirtuin group	Enzyme localization	Enzyme activity
SIRT1	Cytoplasm and nucleus	Deacetylase
SIRT2	Cytoplasm and nucleus	Deacetylase
SIRT3	Cytoplasm, mitochondrion and nucleus	Deacetylase
SIRT4	Mitochondrion	ADP-Ribosyl transferase
SIRT5	Mitochondrion	Deacetylase
SIRT6	Nucleus	Deacetylase and ADP-Ribosyl transferase
SIRT7	Nucleus	Deacetylase

SIRT1: Sirtuin 1.

Citation: Turkmen K, Karagoz A, Kucuk A. Sirtuins as novel players in the pathogenesis of diabetes mellitus. World J Diabetes 2014; 5(6): 894-900
URL: https://www.wjgnet.com/1948-9358/full/v5/i6/894.htm
DOI: https://dx.doi.org/10.4239/wjd.v5.i6.894