Copyright ©2010 Baishideng.
World J Diabetes. May 15, 2010; 1(2): 57-64
Published online May 15, 2010. doi: 10.4239/wjd.v1.i2.57
Figure 2
Figure 2 AT1-R activation by angiotensin II produced by the retina stimulates several pathways involved in the pathogenesis of DR such as inflammation, oxidative stress, leukostasis and angiogenesis. AT1-R:Angiotensin II type 1 receptor; AT2-R: Angiotensin II type 2 receptor; AGEs: Advanced glycated end products; BM: Basal membrane; BRB: Blood retinal barrier; ECM: Extracellular matrix; VEGF: Vascular endothelial growth factor.