Longitudinal effects of Johnson & Johnson COVID-19 vaccination on metabolic biomarkers in type 2 diabetes mellitus in Ethiopia

Figure 1 Triglyceride level over time. A: Average trend of triglyceride (TG) for unvaccinated and vaccinated groups over time. The letter "s" indicates statistically significant differences (P < 0.05) between the groups at each time point, while "ns" denotes no significant difference; B: Effect size of TG for vaccinated groups over time.

Figure 2 High-density lipoprotein level over time. A: Average trend of high-density lipoprotein (HDL) for unvaccinated and vaccinated groups over time. The letter "s" indicates statistically significant differences (P < 0.05) between the groups at each time point, while "ns" denotes no significant difference; B: Effect size of HDL for vaccinated groups over time.

Figure 3 Total cholesterol level over time. A: Average trend of total cholesterol (TC) for unvaccinated and vaccinated groups over time. The letter "s" indicates statistically significant differences (P < 0.05) between the groups at each time point, while "ns" denotes no significant difference; B: Effect size of TC for vaccinated groups over time.

Figure 4 Prostaglandin levels over time. A: Average trend of prostaglandin (PG) for unvaccinated and vaccinated groups. The letter "s" indicates statistically significant differences (P < 0.05) between the groups at each time point, while "ns" denotes no significant difference; B: Effect size of PG for vaccinated groups.

Figure 5 Thromboxane level over time. A: Average trend of thromboxane (TX) for unvaccinated and vaccinated groups over time. The letter "s" indicates statistically significant differences (P < 0.05) between the groups at each time point, while "ns" denotes no significant difference; B: TX for vaccinated groups over time.