Copyright ©The Author(s) 2021.
World J Diabetes. Mar 15, 2021; 12(3): 215-237
Published online Mar 15, 2021. doi: 10.4239/wjd.v12.i3.215
Figure 1
Figure 1 The plausible bidirectional link between diabetes mellitus and coronavirus disease 2019. ACE: Angiotensin-converting enzyme; COVID-19: Coronavirus disease 2019; GLP1A: Glucagon-like peptide-1 receptor agonist; IL: Interleukin; RAAS: Renin-angiotensin-aldosterone system; SARS-CoV-2: Severe acute respiratory syndrome coronavirus 2; SGLT2i: Sodium-glucose cotransporter 2 inhibitors; SIRS: Systemic inflammatory response; TNF: Tumor necrosis factor; TZDS: Thiazolidinediones.
Figure 2
Figure 2 Pathways linking coronavirus disease 2019 to heart/brain injury. Pathway C: Hypoxia pathway. Pathway D: Cytokine storm. Pathway E: Renin-angiotensin-aldosterone system pathway. ACE: Angiotensin-converting enzyme; ARDS: Acute respiratory distress syndrome; IL: Interleukin; SARS-CoV-2: Severe acute respiratory syndrome coronavirus 2; TNF: Tumor necrosis factor.