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©The Author(s) 2016.
World J Gastrointest Oncol. Oct 15, 2016; 8(10): 735-744
Published online Oct 15, 2016. doi: 10.4251/wjgo.v8.i10.735
Published online Oct 15, 2016. doi: 10.4251/wjgo.v8.i10.735
Table 1 Nanomedicine-based therapies against cancer stem cells of the digestive system
| Tumor types | Nanomedicine | Ref. |
| Drug delivery | ||
| Gastric cancer | SAL-loaded carbon nanotubes functionalized with HA | [82] |
| Liver cancer | SAL-loaded iRGD-conjugated DSPE-PEG2000 nanomicelles | [83] |
| Colorectal cancer | Curcumin-loaded CSO-SA micelles | [87] |
| Oxaliplatin-loaded CSO-SA micelles | [88] | |
| Gene delivery | ||
| Liver cancer | anti-EpCAM-monoclonal-antibody-labeled block copolymer vesicle | [89] |
| Colorectal cancer | Wtp53 gene loaded scL nanocomplex | [90] |
| Colon cancer | MDR1 siRNA loaded lipid nanoparticles | [91] |
| Gastric cancer | miR-200c loaded gelatinase-stimuli PEG-Pep-PCL nanoparticles | [94] |
| Targeted delivery | ||
| Gastric cancer | SAL-loaded carbon nanotubes functionalized with HA | [82] |
| Liver cancer | anti-CD44 antibody-mediated liposomal nanoparticle loaded of doxorubicin | [96] |
| CD90-targeted thermosensitive magnetoliposomes-encapsulated 17-AAG | [97] | |
| Combinational delivery | ||
| Gastric cancer | Nanoparticle co-loaded miR-200c and DOC | [99] |
| Liver cancer | micellar nanoparticle co-delivering platinum (IV) prodrug and siNotch1 | [100] |
| Colorectal cancer | Liposomes co-encapsulated irinotecan and floxuridine | [101] |
| Colon cancer | Nanoliposomes co-encapsulated vincristine and topotecan | [102] |
- Citation: Xie FY, Xu WH, Yin C, Zhang GQ, Zhong YQ, Gao J. Nanomedicine strategies for sustained, controlled, and targeted treatment of cancer stem cells of the digestive system. World J Gastrointest Oncol 2016; 8(10): 735-744
- URL: https://www.wjgnet.com/1948-5204/full/v8/i10/735.htm
- DOI: https://dx.doi.org/10.4251/wjgo.v8.i10.735