Clinical characteristics and outcome of primary hepatic neuroendocrine tumors after comprehensive therapy

Table 1 Correlations of tumor grade with clinicopathological characteristics

Parameter	Tumor grade		P value
	G1/G2	G3/NEC
Age (yr)			0.804
< 50	11	6
≥ 50	14	9
Gender			0.622
Male	12	6
Female	13	9
Hypertension			0.914
Yes	5	2
No	20	13
Diabetes			0.711
Yes	4	1
No	21	14
Syn			1.000
Positive	23	15
Negative	1	0
CgA			0.810
Positive	11	6
Negative	7	2
CD56			1.000
Positive	21	14
Negative	1	1
AE1/AE3			0.341
Positive	18	10
Negative	1	3
Ki-67			0.000
≤ 20%	25	2
> 20%	0	13
NSE			0.585
Positive	7	6
Negative	10	4
Tumor number			0.334
Single	6	1
Multiple	19	14
Tumor size (cm)			1.000
≤ 3	3	2
> 3	16	8
Metastasis			0.884
Yes	5	4
No	19	10
Treatment			0.470
Non-surgical treatment	10	9
Surgical treatment	10	4
Mixed treatment	5	2

Table 2 Remission rates of clinical symptoms in all groups

Treatment/symptoms	Pre-treatment (n)	Post-treatment (n)	Remission rate
Non-surgical treatment (19 cases)	23	7	69.6%
Abdominal pain	10	4
Acid reflux	2	0
Vomiting	3	1
Bloating	3	1
Diarrhea	5	1
Surgical treatment (14 cases)	12	2	83.3%
Abdominal pain	5	1
Acid reflux	2	0
Vomiting	3	0
Bloating	1	1
Dizziness	1	0
Mixed treatment (7 cases)	8	2	75.0%
Abdominal pain	4	1
Bloating	4	1