Hepatomegaly and jaundice as the presenting symptoms of systemic light-chain amyloidosis: A case report

Figure 2 Liver pathology and bone marrow aspiration smear. A: Hematoxylin-eosin staining (100 ×) showed deposition of pink fine-grained amorphous material in hepatic lobule and portal area, compression and deformation of liver plates, and atrophy of hepatocytes; B: Masson staining (40 ×) showed mild peri-sinusoidal fibrosis; C: Periodic acid-Schiff staining (40 ×) showed significant atrophy of liver cells with a few residual liver cells; D: Congo red staining (40 ×) indicated brick-red material deposition between liver cells; E and F: Bone marrow aspiration smear (100 ×) showed abnormal proliferation of plasma cell system. The cells are moderate-sized, the nucleus is large and eccentric, round or oval, the nuclear chromatin is fine, the cytoplasm is rich, blue, and foamy (black arrows).