Early results of the integrative epigenomic-transcriptomic landscape of colorectal adenoma and cancer

doi:10.4251/wjgo.v16.i2.414

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World Journal of Gastrointestinal Oncology

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1948-5204

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastrointest Oncol. Feb 15, 2024; 16(2): 414-435
Published online Feb 15, 2024. doi: 10.4251/wjgo.v16.i2.414

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Figure 7 Identification of methylation-silenced genes in the Colon Adenocarcinoma dataset. A: Heatmap of expression level of methylation-regulated differentially expressed genes (meDEGs) in the Colon Adenocarcinoma (COAD) dataset; B: Heatmap of meDEG methylation in the COAD dataset; C: Barplot of ranked correlations between meDEG expression and methylation in the COAD dataset; D: Protein-protein interaction network of the meDEGs, constructed using GeneMANIA; E: Kaplan-Meier plots of overall survival according to AGTR1 methylation; F: Kaplan-Meier plots of overall survival according to NECAB1 methylation. CRC: Colorectal cancer.

Citation: Lu YW, Ding ZL, Mao R, Zhao GG, He YQ, Li XL, Liu J. Early results of the integrative epigenomic-transcriptomic landscape of colorectal adenoma and cancer. World J Gastrointest Oncol 2024; 16(2): 414-435
URL: https://www.wjgnet.com/1948-5204/full/v16/i2/414.htm
DOI: https://dx.doi.org/10.4251/wjgo.v16.i2.414