Response of human epidermal growth factor receptor 2-positive colorectal cancer to lapatinib monotherapy: A case report
Ji-Lin Guan, Jian-Hua Liu, Ling Huang, Department of Oncology, Guangdong Provincial People's Hospital and Guangdong Academy of Medical Sciences, Guangzhou 510655, Guangdong Province, China
Qing Wang, Yu-Wei Cong, Yao-Xu Chen, Meng-Li Huang, The Medical Department, 3D Medicines Inc., Shanghai 201114, China
Ke-Fei Huang, The Bioinformatic Department, 3D Medicines Inc., Shanghai 201114, China
Author contributions: Guan JL, Huang ML, and Huang L contributed to the case report design; Guan JL was the physician in charge who provided the patient’s information; Liu JH provided the histologic images, confirmed the diagnosis, and contributed the details about the histologic diagnosis; Wang Q collected and provided the data; Cong YW, Chen YX, and Huang KF performed NGS testing, formal analysis, and data visualization; Guan JL, Wang Q, and Chen YX were involved in writing, review, and editing of the manuscript; Huang L was the principle author of the paper, had full access to all data, and is the guarantor; Huang ML supervised the report and the publication process; all authors read and confirmed the final version of this article.
Informed consent statement: Written informed consent was obtained from the patient for publication of this case report and any accompanying images.
Conflict-of-interest statement: There is no conflict of interest to disclose.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Ling Huang, MD, Director, Doctor, Professor, Department of Oncology, Guangdong Provincial People's Hospital and Guangdong Academy of Medical Sciences, No. 123 West Huifu Road, Yuexiu District, Guangzhou 510655, Guangdong Province, China. firstname.lastname@example.org
Received: April 22, 2020
Peer-review started: April 22, 2020
First decision: April 26, 2020
Revised: July 16, 2020
Accepted: August 16, 2020
Article in press: August 16, 2020
Published online: September 15, 2020