Incorporation of perigastric tumor deposits into the TNM staging system for primary gastric cancer

Figure 1 Comparison of survival between patients with and without tumor deposits. A: Kaplan-Meier survival curves of patients with and without tumor deposits (TDs); B: Survival months between patients with and without TDs. TDs: Tumor deposits.

Figure 2 Kaplan-Meier survival curves of patients with and without tumor deposits in different TNM stages. A: TNM stage–based survival analysis among postoperative patients without gastric cancer tumor deposits; B: TNM stage–based survival analysis among postoperative patients with gastric cancer tumor deposits.

Figure 3 Overall survival of different TNM stages for patients with and without tumor deposits. A: Stage I patients with and without tumor deposits (TDs); B: Stage II patients with and without TDs; C: Stage III patients with and without TDs; D: Stage IV patients with and without TDs. TDs: Tumor deposits.

Figure 4 Comparison of survival curves of patients with and without tumor deposits in different pathological TNM categories. A: Survival curves of patients with and without tumor deposits (TDs) in the category of pTNM; B: Survival curves of patients with and without TDs in the category of pathological stage of T; C: Survival curves of patients with and without TDs in the category of pathological stage of N; D: Survival curves of patients with and without TDs in the category of pathological stage of M. TDs: Tumor deposits; pT: Pathological stage of T; pN: Pathological stage of N; pM: Pathological stage of M.

Figure 5 Comparison of survival outcomes associated with tumor deposits in different locations. A: Kaplan-Meier survival curves of patients with and without tumor deposits (TDs) in different locations; B: Survival months between patients with TDs in different locations. TDs: Tumor deposits.

Figure 6 Comparison of survival curves of patients with different tumor deposit locations and with those of patients without tumor deposits with different TNM pathological stages. A: Comparison of Kaplan-Meier (K-M) curves of patients with tumor deposits (TDs) appearing in the gastric body with pathological stage of T without TDs; B: Comparison of K-M curves of patients with TDs appearing in the lesser curvature with pathological stage of N without TDs; C: Comparison of K-M curves of patients with TDs appearing in the greater curvature with pathological stage of M (pM) without TDs; D: Comparison of K-M curves of patients with TDs appearing in distant tissue with pM without TDs. TDs: Tumor deposits; pT: Pathological stage of T; pN: Pathological stage of N; pM: Pathological stage of M.

Figure 7 Survival curves generated using the proposed TNM staging framework incorporating tumor deposits. A: Survival curves generated using the new TNM staging framework for patients with gastric cancer tumor deposits (TDs); B: Survival curves of stage II postoperative patients with and without TDs; C: Survival curves of stage III postoperative patients with and without TDs; D: Survival curves of stage IV postoperative patients with and without TDs. TDs: Tumor deposits.