Efficacy of continuous gastric artery infusion chemotherapy in relieving digestive obstruction in advanced gastric cancer

Figure 1 Patients enrollment processes flow diagram.

Figure 2 Overall survival time of advanced gastric cancer patients and subgroup analysis. A: The overall survival time of advanced gastric cancer patients with digestive obstruction after continuous gastric artery infusion chemotherapy (cGAIC). The mOS was 16 mo; B: Subgroup analysis between patients who got obstruction relieved and patients not; C: Subgroup analysis between patients who received radical surgery and patients not. Relief: Patients with digestive obstruction got relieved after cGAIC. Not relief: Patients with digestive obstruction didn’t get relieved after cGAIC. Convert: Initially unresectable gastric cancer patients converted into resectable successfully. Unconvert: Initially unresectable gastric cancer patients failed to convert into resectable.

Figure 3 Comparison between pre and post continuous gastric artery infusion chemotherapy in patient with gastroesophageal junction obstruction. A and B: gastroesophageal junction obstruction (red arrow) in abdominal contrast-enhanced computed tomography (CT) before continuous gastric artery infusion chemotherapy (cGAIC); C and D: C-arm computed tomographic angiography was used to find the tumor-feeding artery accurately in right gastroepiploic artery; E and F: Tumor in gastric fundus shrank obviously, blurred boundary became clear, and blocked digestive tract opened again in gastroesophageal junction (blue arrow), shown in abdominal contrast-enhanced CT in 2 wk after first cGAIC.