Anatomic resection improved the long-term outcome of hepatocellular carcinoma patients with microvascular invasion: A prospective cohort study

doi:10.4251/wjgo.v13.i12.2190

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Dec 15, 2021 (publication date) through May 4, 2024

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World Journal of Gastrointestinal Oncology

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1948-5204

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Prospective Study

World J Gastrointest Oncol. Dec 15, 2021; 13(12): 2190-2202
Published online Dec 15, 2021. doi: 10.4251/wjgo.v13.i12.2190

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Figure 1 Flow diagram for the study. AR: Anatomic resection; MVI: Microvascular invasion; NAR: Non-anatomic resection.

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Figure 2 The long-term outcome of hepatocellular carcinoma with different tumor diameters. A: Kaplan-Meier analysis of the overall survival (OS) in microvascular invasion (MVI) positive and MVI negative patients with a tumor diameter 2-5 cm; B: In the group with a tumor diameter of 2-5 cm, Kaplan-Meier analysis of the OS in receiving MVI positive anatomic resection (AR) and non-anatomic resection (NAR) patients; C: In the group with a tumor diameter of 2-5 cm, Kaplan-Meier analysis of the OS in receiving AR and NAR patients with MVI negative. D: Kaplan-Meier analysis of the OS in MVI positive and MVI negative patients with a tumor diameter of less than 2 cm.

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Figure 3 The long-term outcome of hepatocellular carcinoma with different tumor diameter. A: In the group with a tumor diameter of less than 2 cm, Kaplan-Meier analysis of the overall survival (OS) in receiving anatomic resection (AR) and non-anatomic resection (NAR) patients with microvascular invasion (MVI) positive; B: In the group with a tumor diameter of less than 2 cm, Kaplan-Meier analysis of the OS in patients receiving AR and NAR patients who were MVI negative; C: Kaplan-Meier analysis of the OS in MVI positive and MVI negative patients with tumor diameters larger than 5 cm; D: In the group with a tumor diameter of larger than 5 cm, Kaplan-Meier analysis of the OS in MVI positive patients receiving AR and NAR.

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Figure 4 Kaplan-Meier analysis of the overall survival (A) and comparison of surgical margins in patients with different tumor diameters (B). A: In the group with a tumor diameter larger than 5 cm, Kaplan-Meier analysis of the overall survival in microvascular invasion negative patients receiving anatomic resection (AR) and non-anatomic resection (NAR); B: Comparison of surgical margins in patients receiving AR and NAR with different tumor diameters.

Citation: Zhou JM, Zhou CY, Chen XP, Zhang ZW. Anatomic resection improved the long-term outcome of hepatocellular carcinoma patients with microvascular invasion: A prospective cohort study. World J Gastrointest Oncol 2021; 13(12): 2190-2202
URL: https://www.wjgnet.com/1948-5204/full/v13/i12/2190.htm
DOI: https://dx.doi.org/10.4251/wjgo.v13.i12.2190