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Copyright ©The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Oncol. Apr 15, 2016; 8(4): 351-357
Published online Apr 15, 2016. doi: 10.4251/wjgo.v8.i4.351
Status of colitis-associated cancer in ulcerative colitis
Tetsushi Kinugasa, Yoshito Akagi
Tetsushi Kinugasa, Yoshito Akagi, Department of Surgery, Kurume University School of Medicine, Fukuoka 830-0011, Japan
Author contributions: Kinugasa T contributed to concept and design; both authors contributed to this paper.
Conflict-of-interest statement: Authors declare no conflict of interests for this article.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See:
Correspondence to: Dr. Tetsushi Kinugasa, Department of Surgery, Kurume University School of Medicine, 67 Asahi-machi, Kurume, Fukuoka 830-0011, Japan.
Telephone: +81-942-353311 Fax: +81-942-340709
Received: April 28, 2015
Peer-review started: May 5, 2015
First decision: July 1, 2015
Revised: January 24, 2016
Accepted: February 16, 2016
Article in press: February 17, 2016
Published online: April 15, 2016
Core Tip

Core tip: Inflammatory bowel disease, especially ulcerative colitis, is an important risk factor for development of colon cancer. There has been quite increased in the number of patients who had high-grade dysplasia and/or cancer. The relationship between inflammation and tumorigenesis is well-established and in the last decade has received a great deal of supporting evidence from genetic, pharmacological, and epidemiological data. To avoid such a problem, there is a need for appropriate diagnosis and treatment. It should be considered that actively introduce the surgical treatment in addition to medical treatment.