Published online Aug 15, 2015. doi: 10.4251/wjgo.v7.i8.111
Peer-review started: January 16, 2015
First decision: April 24, 2015
Revised: April 30, 2015
Accepted: July 7, 2015
Article in press: July 8, 2015
Published online: August 15, 2015
Core tip: Recently, it has become clear that an elevated systemic inflammatory response is consistently associated with a poor outcome, independent of the tumor stage. The inflammatory response is represented by the levels of serum neutrophils, lymphocytes and platelet s as well as acute-phase proteins and their combinations. These parameters are simple and easy to measure using widely available standardized assays. In this review, we discuss the prognostic value of various inflammation-based factors in patients with colorectal cancer.