Topic Highlight
Copyright ©The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Oncol. Oct 15, 2015; 7(10): 233-240
Published online Oct 15, 2015. doi: 10.4251/wjgo.v7.i10.233
Relationship between intestinal microbiota and colorectal cancer
Gokhan Cipe, Ufuk Oguz Idiz, Deniz Firat, Huseyin Bektasoglu
Gokhan Cipe, Department of General Surgery, Fatih University, Istanbul 34844, Turkey
Ufuk Oguz Idiz, Deniz Firat, Huseyin Bektasoglu, Department of General Surgery, Bezmialem Vakif University, Istanbul 34093, Turkey
Author contributions: Cipe G and Idiz UO contributed equally to this work; Cipe G, Idiz UO, Firat D and Bektasoglu H designed the research; Idiz UO and Firat D performed the research; Idiz UO, Firat D and Bektasoglu H wrote the paper.
Conflict-of-interest statement: The authors declare that they have no conflict of interest.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Gokhan Cipe, Associate Professor, Department of General Surgery, Fatih University, Yalı Mah. Sahil Yolu Sk. No:16, Dragos, Istanbul 34844, Turkey. gokhancipe@hotmail.com
Telephone: +90-50-53743429
Received: April 29, 2015
Peer-review started: May 12, 2015
First decision: July 6, 2015
Revised: August 2, 2015
Accepted: September 7, 2015
Article in press: September 8, 2015
Published online: October 15, 2015
Core Tip

Core tip: Microbiota’s role in providing intestinal homeostasis is not as an audience, but it is active. Both the composition of microbiota and its metabolic activity impact the sensitivity of the host and can cause many pathologies including colorectal cancer.