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World J Gastrointest Oncol. May 15, 2014; 6(5): 139-144
Published online May 15, 2014. doi: 10.4251/wjgo.v6.i5.139
Published online May 15, 2014. doi: 10.4251/wjgo.v6.i5.139
Prognostic value of baseline FDG uptake on PET-CT in esophageal carcinoma
Omar S Al-Taan, Amar Eltweri, David Sharpe, Sukhbir S Ubhi, David J Bowrey, Departments of Surgery, University Hospitals of Leicester, Leicester LE1 5WW, United Kingdom
Peter M Rodgers, Departments of Radiology, University Hospitals of Leicester, Leicester LE1 5WW, United Kingdom
Author contributions: Ubhi SS and Bowrey DJ designed the research; Eltweri A and Sharpe D performed the research; Sharpe D and Bowrey DJ analyzed data; Al-Taan OS, Rodgers PM, Ubhi SS and Bowrey DJ wrote the paper.
Correspondence to: Dr. David J Bowrey, Consultant Surgeon and Honorary Senior Lecturer, Department of Surgery, University Hospitals of Leicester, Level 6 Balmoral Building, Leicester Royal Infirmary, Leicester LE1 5WW, United Kingdom. djb57@le.ac.uk
Telephone: +44-116-2585247 Fax: +44-116-2586083
Received: November 12, 2013
Revised: February 19, 2014
Accepted: April 11, 2014
Published online: May 15, 2014
Revised: February 19, 2014
Accepted: April 11, 2014
Published online: May 15, 2014
Core Tip
Core tip: Positron emission tomography-computed tomography (PET-CT) is integral to the staging of esophageal cancer. It is unclear whether the value of PET-CT extends beyond the identification of metastatic disease. The influence of PET-CT maximum standardized uptake value (SUVmax) on prognosis was determined for 271 patients. Although SUVmax was closely linked to disease stage, it did not exert an independent effect and was not a useful prognostic marker.