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World J Gastrointest Oncol. Jul 15, 2013; 5(7): 147-158
Published online Jul 15, 2013. doi: 10.4251/wjgo.v5.i7.147
Outcome of surgical resection in Klatskin tumors
Alejandro Serrablo, Luis Tejedor
Alejandro Serrablo, Medicine School of Zaragoza University, HPB Surgical Unit, Miguel Servet University Hospital, 50009 Zaragoza, Spain
Luis Tejedor, General Surgery Department, Punta Europa Hospital, 11207 Algeciras, Spain
Author contributions: All authors contributed equally to this work.
Correspondence to: Alejandro Serrablo, MD, PhD, Associate Professor of Surgery, Medicine School of Zaragoza University, HPB Surgical Unit, Miguel Servet University Hospital, Isabel la Catolica 1-3, 50009 Zaragoza, Spain. almaley@telefonica.net
Telephone: +34-97-6765500 Fax: +34-97-6765558
Received: February 22, 2013
Revised: April 10, 2013
Accepted: April 28, 2013
Published online: July 15, 2013
Core Tip

Core tip: Klatskin described the specific clinical characteristics in 1965, and the tumor is often referred to as Klatskin tumor. Cholangiocarcinomas (CC) are the second most frequent primary hepatic malignancy. Hilar cholangiocarcinoma (HCC) is the most common type, and accounts most of CC cases. These tumors are slowly growing, and have a tendency to local spread and infrequent distant metastases. The most common presentation is with the onset of jaundice. The majority of HCC are small infiltrating tumors. Long-term survival in patients with HCC depends critically on complete tumor resection. This work is an important update concerning outcome of surgical management in Klatskin tumors.