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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.
World J Gastrointest Oncol. Oct 15, 2026; 18(10): 123966
Published online Oct 15, 2026. doi: 10.4251/wjgo.123966
Integrating traditional Chinese medicine with pancreatic cancer organoids: Bibliometric insights and translational perspectives
Qing-Ze Chen, Xiang Chi, Jia-Hao Pan, Qi-Zhi Cheng, Yi-Jun Guo, Yi-Xuan Liu, Lu Yu, Wei-Ke Feng
Qing-Ze Chen, Xiang Chi, Qi-Zhi Cheng, Yi-Jun Guo, Yi-Xuan Liu, Lu Yu, College of Traditional Chinese Medicine, Shandong University of Traditional Chinese Medicine, Jinan 250355, Shandong Province, China
Jia-Hao Pan, International College of Ophthalmology and Optometry, Shandong University of Traditional Chinese Medicine, Jinan 250002, Shandong Province, China
Wei-Ke Feng, College of Medicine, Shandong University of Traditional Chinese Medicine, Jinan 250355, Shandong Province, China
Author contributions: Chen QZ initiated the study, wrote the original manuscript and completed visualization and validation; Chen QZ and Chi X conceived this study; Pan JH obtained and analyzed the data; Cheng QZ and Guo YJ completed software acquisition and literature retrieval; Liu YX and Yu L were responsible for the entire research process management; Feng WK reviewed and edited the manuscript and secured funding; all authors have read and approved the final manuscript.
AI contribution statement: The authors declare that no AI tools were used in the development or writing of this manuscript and take full responsibility for its integrity, accuracy, and originality.
Conflict-of-interest statement: All authors declare no conflict of interest in publishing the manuscript.
PRISMA 2009 Checklist statement: The authors have read the PRISMA 2009 Checklist, and the manuscript was prepared and revised according to the PRISMA 2009 Checklist.
Corresponding author: Wei-Ke Feng, Associate Professor, College of Medicine, Shandong University of Traditional Chinese Medicine, No. 4655 University Road, Changqing District University Science and Technology Park, Jinan 250355, Shandong Province, China. fengweike315@163.com
Received: June 2, 2026
Revised: July 7, 2026
Accepted: July 27, 2026
Published online: October 15, 2026
Processing time: 111 Days and 23.7 Hours
Core Tip

Core Tip: Pancreatic cancer is difficult to treat. Recently, scientists have started using organoids as a tool for testing new cancer drugs. Natural compounds from traditional Chinese medicine show potential because they can attack cancer cells in multiple ways. We analyzed > 1000 scientific papers to determine if researchers are using these advanced three-dimensional models to test traditional medicines. There was little research combining these two promising fields. By revealing this gap, we aim to encourage the scientific community to use patient-specific tumor models to evaluate natural medicines. This integration could accelerate the discovery of new, personalized treatments for pancreatic cancer, bridging the gap between natural remedies and modern precision medicine.

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