Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.
World J Gastrointest Oncol. Oct 15, 2026; 18(10): 121749
Published online Oct 15, 2026. doi: 10.4251/wjgo.121749
Published online Oct 15, 2026. doi: 10.4251/wjgo.121749
Effects of stepwise lipid-controlled enteral nutrition on lipids and nutrition in hyperlipidemic acute pancreatitis with colorectal cancer
Peng Chen, Xiang-Cheng Dai, Department of Infectious Diseases, Yichang Central People’s Hospital, Yichang 443000, Hubei Province, China
Hui-Min Qin, Department of Medical Affairs, Yichang Central People’s Hospital, Yichang 443000, Hubei Province, China
Author contributions: Chen P contributed to research design and data collection; Dai XC contributed to data analysis and paper writing; Qin HM was responsible for research design, funding application, data analysis, reviewing and editing, communication coordination, ethical review, copyright and licensing, and follow-up; and all authors have read and approve the final manuscript.
AI contribution statement: This article did not utilize any artificial intelligence tools for proofreading, generating research data, interpreting results or forming conclusions. All the outputs generated by artificial intelligence were rigorously reviewed and revised by the author.
Institutional review board statement: The research was reviewed and approved by the Clinical Trial Ethics Committee of the Yichang Central People’s Hospital.
Informed consent statement: All research participants or their legal guardians provided written informed consent prior to study registration
Conflict-of-interest statement: No conflict of interest is associated with this work.
Data sharing statement: No other data available.
Corresponding author: Hui-Min Qin, Chief Physician, Department of Medical Affairs, Yichang Central People’s Hospital, No. 183 Yiling Avenue, Yichang 443000, Hubei Province, China. chenp2099@163.com
Received: April 17, 2026
Revised: May 8, 2026
Accepted: June 8, 2026
Published online: October 15, 2026
Processing time: 153 Days and 1.5 Hours
Revised: May 8, 2026
Accepted: June 8, 2026
Published online: October 15, 2026
Processing time: 153 Days and 1.5 Hours
Core Tip
Core Tip: This intervention study demonstrates that a stepwise lipid-controlled enteral nutrition protocol, dynamically adjusted based on triglyceride (TG) thresholds, significantly reduces hypertriglyceridemia, optimizes concurrent lipid and protein metabolism, and accelerates clinical recovery in patients with hyperlipidemic acute pancreatitis and colorectal cancer. The findings advocate for integrating dynamic lipid monitoring into nutritional management for such complex comorbidities and propose a “TG-guided, protein-prioritized” enteral nutrition model, addressing a critical gap in the metabolic support of oncological patients with acute metabolic inflammation.