Letter to the Editor
Copyright ©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Oncol. Jun 15, 2025; 17(6): 100010
Published online Jun 15, 2025. doi: 10.4251/wjgo.v17.i6.100010
Prognostic impact of inflammatory and nutritional markers in colorectal cancer patients with peritoneal metastasis
Zhao Cai, Wei-De Dai, Xiong-Wei Cai
Zhao Cai, Wei-De Dai, Department of Ultrasound, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing 100005, China
Xiong-Wei Cai, Department of Gynecology, Chongqing Health Center for Women and Children, Women and Children’s Hospital of Chongqing Medical University, Chongqing 410013, China
Author contributions: Cai Z contributed to the writing and review of literature; Cai Z, Dai WD, and Cai XW contributed to editing the manuscript; Cai Z, Dai WD, and Cai XW contributed to the overall conception and outline design of the manuscript; and all authors thoroughly reviewed and endorsed the final manuscript.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Xiong-Wei Cai, PhD, Department of Gynecology, Chongqing Health Center for Women and Children, Women and Children’s Hospital of Chongqing Medical University, No. 1 Yixueyuan Road, Yuzhong District, Chongqing 410013, China. xiongweicai@126.com
Received: August 7, 2024
Revised: January 23, 2025
Accepted: February 11, 2025
Published online: June 15, 2025
Processing time: 310 Days and 2.4 Hours
Core Tip

Core Tip: Colorectal cancer (CRC) remains a major global health challenge, with metastasis posing a critical obstacle to treatment and patient management. Preoperative inflammatory and nutritional markers have been identified as independent prognostic markers for CRC patients with peritoneal metastasis. When combined with age, carbohydrate antigen 199 levels, and the peritoneal cancer index, these markers provide a reliable method for predicting overall survival. This combination offers a promising tool for predicting the prognosis and guiding the treatment of CRC with peritoneal metastasis.