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©The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Oncol. Jun 15, 2020; 12(6): 632-641
Published online Jun 15, 2020. doi: 10.4251/wjgo.v12.i6.632
Published online Jun 15, 2020. doi: 10.4251/wjgo.v12.i6.632
Low ligation has a lower anastomotic leakage rate after rectal cancer surgery
Jia-Nan Chen, Zheng Liu, Zhi-Jie Wang, Fu-Qiang Zhao, Fang-Ze Wei, Shi-Wen Mei, Hai-Yu Shen, Juan Li, Wei Pei, Zheng Wang, Qian Liu, Department of Colorectal Surgery, National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union College, Beijing 100021, China
Jun Yu, Department of Surgery, the Johns Hopkins University School of Medicine, Baltimore, MD 21218, United States
Author contributions: Chen JN, Zhao FQ, and Wang ZJ designed the research; Mei SW, Shen HY, Wei FZ and Li J collected the data; Pei W, Wang Z, Liu Z analyzed the data; Chen JN drafted the article; Liu Q and Yu J revised the paper.
Supported by the Medicine and Health Technology Innovation Project of Chinese Academy of Medical Sciences , No. 2017-12M-1-006 ; and China Scholarship Council , No. CSC201906210471 .
Institutional review board statement: Our investigation received approval from the ethics committee of the National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College.
Informed consent statement: All patients signed informed consent forms.
Conflict-of-interest statement: The authors declare there is no conflict of interest in regard to this research.
Data sharing statement: No additional data are available.
STROBE statement: The authors have carefully read the STROBE statement checklist of items and prepared the manuscript based on the requirements of the STROBE statement checklist of items.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Qian Liu, MD, Chief Doctor, Professor, Surgeon, Department of Colorectal Surgery, National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, No. 17 Panjiayuan Nanli, Chaoyang District, Beijing 100021, China. fcwpumch@163.com
Received: January 11, 2020
Peer-review started: January 11, 2020
First decision: April 7, 2020
Revised: May 13, 2020
Accepted: May 14, 2020
Article in press: May 14, 2020
Published online: June 15, 2020
Peer-review started: January 11, 2020
First decision: April 7, 2020
Revised: May 13, 2020
Accepted: May 14, 2020
Article in press: May 14, 2020
Published online: June 15, 2020
Core Tip
Core tip: Anastomotic leakage (AL) is one of the most common and serious postoperative complications of colorectal surgery and is a major cause of postoperative mortality and morbidity. Our study shows that low ligation of the inferior mesenteric artery in rectal cancer patients has a lower AL rate and diverting stoma rate. Older age and tumor located below the peritoneal reflection are also risk factors for AL. In rectal cancer surgery, low ligation should be the preferred method.