Copyright
©The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Oncol. Jan 15, 2020; 12(1): 92-100
Published online Jan 15, 2020. doi: 10.4251/wjgo.v12.i1.92
Published online Jan 15, 2020. doi: 10.4251/wjgo.v12.i1.92
Simultaneous transarterial chemoembolization and radiofrequency ablation for large hepatocellular carcinoma
Feng Duan, Yan-Hua Bai, Li Cui, Xiao-Hui Li, Jie-Yu Yan, Mao-Qiang Wang, Department of Interventional Radiology, General Hospital of Chinese People’s Liberation Army, Beijing 100853, China
Author contributions: Duan F and Wang MQ designed research; Duan F, Li XH, Yan JY, Wang MQ performed clinical research; Bai YH and Cui L analyzed data; Duan F and Cui L wrote the paper, all authors read and approved the final manuscript.
Institutional review board statement: This study was reviewed and approved by the General Hospital of People’s Liberation Army Institutional Review Board.
Informed consent statement: Patients were not required to give informed consent to the study because the analysis used anonymous data.
Conflict-of-interest statement: The authors declare that there are no conflicts of interest related to this article.
Data sharing statement: No additional unpublished data are available.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Mao-Qiang Wang, MD, PhD, Professor, Department of Interventional Radiology, General Hospital of Chinese People’s Liberation Army, No. 28 Fuxing Road, Haidian District, Beijing 100853, China. wangmq@vip.sina.com
Received: September 5, 2019
Peer-review started: September 5, 2019
First decision: October 18, 2019
Revised: October 25, 2019
Accepted: December 6, 2019
Article in press: December 6, 2019
Published online: January 15, 2020
Peer-review started: September 5, 2019
First decision: October 18, 2019
Revised: October 25, 2019
Accepted: December 6, 2019
Article in press: December 6, 2019
Published online: January 15, 2020
Core Tip
Core tip: Hepatocellular carcinoma (HCC) is a common cancer and a leading cause of tumor-related death. Patients who have large HCC (≥ 8 cm) are at advanced stages and have poor prognosis. Interventional treatment including transcatheter arterial chemoembolization (TACE) and radiofrequency ablation (RFA) are commonly used for HCC. However, for patients with large HCC, the use of TACE alone and RFA alone can only lead to partial tumor necrosis with poor local control. Our study showed that simultaneous combination of TACE and RFA may improve therapeutic efficacy and survival for patients with large HCC.