Published online Sep 15, 2018. doi: 10.4251/wjgo.v10.i9.260
Peer-review started: March 29, 2018
First decision: April 26, 2018
Revised: June 14, 2018
Accepted: June 26, 2018
Article in press: June 27, 2018
Published online: September 15, 2018
Core tip: Gastric cancer is a common, worldwide malignancy that has a poor prognosis. The promising regulatory potential of long non-coding RNAs (lncRNAs) in tumorigenesis and cancer development, including gastric cancer, has been widely demonstrated. Thus, exploring the function of lncRNAs can help to both gain a better understanding of the pathogenesis and develop novel treatments for gastric cancer. In this review, we aim to elucidate the expression patterns and functional roles of lncRNAs in gastric cancer, and analyze the latent applications of lncRNAs as diagnostic markers and therapeutic targets.