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World J Gastrointest Oncol. Jul 15, 2018; 10(7): 184-193
Published online Jul 15, 2018. doi: 10.4251/wjgo.v10.i7.184
Prediction of malignancy and adverse outcome of solid pseudopapillary tumor of the pancreas
Li You, Feng Yang, De-Liang Fu
Li You, Feng Yang, De-Liang Fu, Department of Pancreatic Surgery, Pancreatic Disease Institute, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai 200040, China
Author contributions: You L contributed to data acquisition, drafting the article, and final approval of the version to be published; Yang F contributed to the conception and design of this paper, data acquisition, drafting and revising the article, and final approval of the version to be published; Fu DL contributed to the conception and design of this paper, and final approval of it.
Conflict-of-interest statement: We declare no conflicts of interest.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Feng Yang, MD, PhD, Associate Professor, Surgeon, Surgical Oncologist, Department of Pancreatic Surgery, Pancreatic Disease Institute, Huashan Hospital, Shanghai Medical College, Fudan University, 12 Central Urumqi Road, Shanghai 200040, China. yffudan98@126.com
Telephone: +86-21-52887164 Fax: +86-21-52888277
Received: March 16, 2018
Peer-review started: March 16, 2018
First decision: April 9, 2018
Revised: April 23, 2018
Accepted: May 23, 2018
Article in press: May 23, 2018
Published online: July 15, 2018
Core Tip

Core tip: Solid pseudopapillary tumor of the pancreas (SPTP) is a heterogeneous tumor, with a small percentage of patients harboring aggressive behaviors. Its prognosis is generally good, with cases having a chance for long-term survival even with recurrence and/or metastasis after surgical resection. The lack of a predictive staging classification that accurately describes the heterogeneity of this disease hinders meaningful research into optimal individualized therapy. Here we summarize and discuss the associated factors proposed for appraisal of the malignant potential and adverse outcome of SPTP.