Published online May 15, 2018. doi: 10.4251/wjgo.v10.i5.115
Peer-review started: February 7, 2018
First decision: March 15, 2018
Revised: March 23, 2018
Accepted: April 15, 2018
Article in press: April 16, 2018
Published online: May 15, 2018
Core tip: Although helicobacter pylori (H. pylori) infection is the most important risk factor for gastric cancer (GC) development, eradication of this bacteria does not guarantee the elimination of GC risk, as pre-neoplastic lesions may have already developed. It is therefore necessary to identify patients at high-risk for GC after H. pylori eradication by either endoscopy with histologic assessment or non-invasive testing. Long-term endoscopic surveillance is advisable for high-risk patients. Future studies are necessary to investigate medications that may modify the GC risk after H. pylori eradication.