Published online Jan 15, 2021. doi: 10.4251/wjgo.v13.i1.24
Peer-review started: September 8, 2020
First decision: October 21, 2020
Revised: November 3, 2020
Accepted: November 29, 2020
Article in press: November 29, 2020
Published online: January 15, 2021
Positive peritoneal wash cytology with no peritoneal metastasis (CY1P0) is a special distant metastasis of gastric cancer, and currently there are no extensive treatment guidelines for patients with CY1P0 gastric cancer.
To assess survival after radical gastrectomy for CY1P0 gastric cancer and to identify factors associated with long-term prognosis.
To evaluate the effect of radical gastrectomy on survival in patients with CY1P0 gastric cancer, and to identify prognostic risk factors.
Our study included 48 patients with primary CY1P0 gastric cancer who had radical gastrectomies. Overall survival (OS) statistics were available for 48 patients. Follow-up continued through March 2020. Univariate and multivariate analyses were performed using a Cox proportional hazards model to identify prognostic factors.
For the 48 CY1P0 patients, median OS was 22.0 mo, while the OS of patients who received chemotherapy alone was 9.9-12.6 mo. Pathological N factor (P = 0.001) and vascular invasion (P = 0.031) were significant independent risk factors for OS.
This study illustrated the efficacy of radical gastrectomy for CY1P0 gastric cancer patients. More effective treatment should be established for patients who are diagnosed with pN3b disease and vascular invasion.
To formulate the standard treatment plan for CY1P0 gastric cancer.