Editorial
Copyright ©The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Oncol. Oct 15, 2017; 9(10): 402-406
Published online Oct 15, 2017. doi: 10.4251/wjgo.v9.i10.402
New endoscopy advances to refine adenoma detection rate for colorectal cancer screening: None is the winner
Marcello Maida, Salvatore Camilleri, Michele Manganaro, Serena Garufi, Giuseppe Scarpulla
Marcello Maida, Salvatore Camilleri, Michele Manganaro, Serena Garufi, Giuseppe Scarpulla, Section of Gastroenterology, S. Elia - M. Raimondi Hospital, 93100 Caltanissetta, Italy
Author contributions: All authors contributed to writing the paper and had full control over preparation of manuscript; all authors approved the final draft manuscript.
Conflict-of-interest statement: All authors declare no conflict of interest related to this publication.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Marcello Maida, MD, Section of Gastroenterology, S. Elia - M. Raimondi Hospital, Via G. Cusmano 1, 93100 Caltanissetta, Italy. marcello.maida@unipa.it
Telephone: +39-9-34512247 Fax: +39-9-34512340
Received: June 2, 2017
Peer-review started: June 12, 2017
First decision: July 11, 2017
Revised: July 14, 2017
Accepted: July 21, 2017
Article in press: July 24, 2017
Published online: October 15, 2017
Processing time: 129 Days and 17.8 Hours
Abstract

Colorectal cancer (CRC) is the third most common cancer in males and second in females, and globally the fourth cause for cancer death worldwide. Oncological screening of CRC has a major role in the management of the disease and it is mostly performed by colonoscopy. Anyway, effectiveness of endoscopic screening for CRC strictly depends on adequate detection and removal of potentially precancerous lesions, and accuracy of colonoscopy in detection of adenomas is still suboptimal. For this reason, several technological advances have been implemented in order to improve the diagnostic sensitivity of colonoscopy in adenoma detection. Among these: (1) Visual technologies such as chromoendoscopy and narrow band imaging; (2) optical innovation as high definition endoscopy, full-spectrum endoscopy or Third Eye Retroscope; and (3) mechanical advances as Cap assisted colonoscopy, Endocuff, Endoring and G-Eye endoscope. All these technologies advances have been tested over time by clinical studies with mixed results. Which of them is more likely to be successful in the next future?

Keywords: Colorectal cancer screening; Colonoscopy; Adenoma detection rate; Diagnostic advances

Core tip: Oncological screening of colorectal cancer is mostly performed by colonscopy and effectiveness of this technique strictly depends on adequate detection and removal of potentially precancerous lesions. Anyway, accuracy of colonoscopy in detection of adenomas is still suboptimal. For this reasons several technological advances have been implemented in order to improve the diagnostic sensitivity of colonoscopy in adenoma detection. Which of them is more likely to be successful in the next future?