Case Report
Copyright ©The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Oncol. Nov 15, 2016; 8(11): 801-804
Published online Nov 15, 2016. doi: 10.4251/wjgo.v8.i11.801
Case of pseudo-Meigs' syndrome caused by gastric cancer-related metastatic ovarian tumor with prolonged survival
Masaru Okamoto, Kazunori Maeda, Atsushi Yanagitani, Kiwamu Tanaka
Masaru Okamoto, Department of General Internal Medicine, Tottori Prefectural Central Hospital, Tottori 680-0901, Japan
Kazunori Maeda, Atsushi Yanagitani, Kiwamu Tanaka, Department of Gastroenterology, Tottori Prefectural Central Hospital, Tottori 680-0901, Japan
Author contributions: Okamoto M, Maeda K, Yanagitani A and Tanaka K equally discussed the clinical manifestations; Maeda K, Yanagitani A and Tanaka K reviewed the manuscript critically; Okamoto M wrote the paper.
Institutional review board statement: Tottori Prefectural Central Hospital Clinical Ethics Review Board does not require approval for case reports.
Informed consent statement: The patient involved in this case report authorized the disclosure of her protected health information for academic purposes.
Conflict-of-interest statement: All authors have no conflicts of interests to declare.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See:
Correspondence to: Masaru Okamoto, MD, Department of General Internal Medicine, Tottori Prefectural Central Hospital, Tottori, Edu, Tottori City, Tottori 680-0901, Japan.
Telephone: +81-857-262271 Fax: +81-857-293227
Received: May 31, 2016
Peer-review started: June 1, 2016
First decision: August 10, 2016
Revised: August 25, 2016
Accepted: September 13, 2016
Article in press: September 18, 2016
Published online: November 15, 2016

A 48-year-old woman presented with bilateral enlarged ovaries, ascites, bilateral pleural effusion, and advanced gastric cancer. Pleural fluid cytology did not reveal malignant cells. Oophorectomy, performed as a palliative procedure, was followed by rapid resolution of the pleural effusion and ascites. The patient was diagnosed with pseudo-Meigs’ syndrome, and underwent chemotherapy followed by partial gastrectomy. At the last follow-up, 84 mo following oophorectomy, she was alive, and free of disease recurrence, despite not receiving any further treatment. Pseudo-Meigs’ syndrome should be considered in patients with bilateral ovarian tumors, ascites and pleural effusion, and treatment such as oophorectomy may result in symptomatic improvement and better prognosis in similar patients.

Keywords: Pseudo-Meigs’ syndrome, Ovarian tumor, Gastric cancer, Pleural effusion, Ascites

Core tip: In general, the prognosis of gastric cancer with distant metastases is poor. On the other hand, oophorectomy for gastric cancer-related metastatic ovarian tumors may improve survival, especially in the absence of metastasis to other organs. We here report a long-term survival case of pseudo-Meigs’ syndrome caused by gastric cancer following oophorectomy. We conclude that pseudo-Meigs’ syndrome should be considered in patients with gastric cancer with enlarged ovaries, pleural effusion, and ascites.