Brief Article
Copyright ©2012 Baishideng. All rights reserved.
World J Gastrointest Oncol. Jul 15, 2012; 4(7): 176-180
Published online Jul 15, 2012. doi: 10.4251/wjgo.v4.i7.176
Cutaneous metastases secondary to pancreatic cancer
Kei Horino, Hiroshi Takamori, Yoshiaki Ikuta, Osamu Nakahara, Akira Chikamoto, Takatoshi Ishiko, Toru Beppu, Hideo Baba
Kei Horino, Hiroshi Takamori, Yoshiaki Ikuta, Osamu Nakahara, Akira Chikamoto, Takatoshi Ishiko, Toru Beppu, Hideo Baba, Department of Gastroenterological Surgery, Graduate School of Medical Sciences, Kumamoto University, 1-1-1 Honjo, Kumamoto 860-8556, Japan
Author contributions: Horino K and Takamori H performed the majority of the study and wrote the manuscript; Ikuta Y, Nakahara O, Chikamoto A, Ishiko T and Beppu T provided analytical tools and the collection of all the human material and were also involved in editing the manuscript; Baba H designed the study.
Correspondence to: Hideo Baba, Professor, Department of Gastroenterological Surgery, Graduate School of Medical Sciences, Kumamoto University, 1-1-1 Honjo, Kumamoto 860-8556, Japan. horino@tamana-chp.jp
Telephone: +81-96-3735213 Fax: +81-96-3714378
Received: November 30, 2011
Revised: July 10, 2012
Accepted: July 12, 2012
Published online: July 15, 2012
Abstract

AIM: To evaluate prognoses after cutaneous metastases, derived from pancreatic cancer.

METHODS: We treated two patients with cutaneous metastases from pancreatic cancer. We reviewed 40 reported patients in addition to our cases and analyzed clinical features of cutaneous metastases from pancreatic cancer.

RESULTS: The median survival time (MST) was 5 mo after diagnoses of cutaneous metastases. The cumulative 2-year survival rate was 3.5%. The most frequent site of cutaneous metastases was the umbilicus. The MST of patients who were treated with chemotherapy or chemoradiotherapy (CRT) was 6.5 mo, which was statistically longer in comparison to patients without treatment. Prognoses of cutaneous metastases are similar to other metastatic sites from pancreatic cancer. Receiving chemotherapy or CRT was the only prognostic factor of cutaneous metastases from pancreatic cancer.

CONCLUSION: The prognoses of cutaneous metastases are similar to other metastatic pancreatic cancers. Receiving chemotherapy or CRT was the only prognostic factor of cutaneous metastases from pancreatic cancer.

Keywords: Cutaneous, Metastasis, Pancreas, Cancer, Prognosis