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World J Gastrointest Oncol. Apr 15, 2012; 4(4): 82-83
Published online Apr 15, 2012. doi: 10.4251/wjgo.v4.i4.82
Colorectal cancer screening: Time for action in Iran
Mohamad Amin Pourhoseingholi, Mohammad Reza Zali
Mohamad Amin Pourhoseingholi, Mohammad Reza Zali, Research Center of Gastroenterology and Liver diseases, Shahid Beheshti University of Medical Sciences, Tehran 1985711151, Iran
Author contributions: The two authors contributed equally in manuscript writing.
Correspondence to: Mohammad Reza Zali, Professor, Research Center of Gastroenterology and Liver diseases, Shahid Beheshti University of Medical Sciences, Tehran 1985711151, Iran. aminphg@gmail.com
Telephone: +98-21-22432515 Fax: +98-21-22432517
Received: May 18, 2011
Revised: March 3, 2012
Accepted: March 10, 2012
Published online: April 15, 2012
Abstract

Colorectal cancer (CRC) is now the third most common cause of cancer-related deaths in the world. According to the Iranian Annual National Cancer Registration Report, CRC is the third most common cancer in Iranian women and fifth in men. The incidence of CRC has increased during the last 25 years. CRC screening is an efficient way to reduce the burden of CRC through detection of precursor lesions of cancer or early stage cancer. Iran may benefit even more from screening programs. According to recent studies, the prevalence of colorectal adenoma in first degree relatives of patients diagnosed with CRC is significantly higher than in the average risk population. So, appropriate screening strategies, especially in relatives of patients, should be considered as the first step of CRC screening in Iran.

Keywords: Colorectal cancer, Screening, Prevention, Relatives, Iran