Zhang S, Li WC, Liu J, Tang Y, Niu DY. Effect of Nutrition Risk Screening 2002-guided enteral nutrition on nutritional status in gastrointestinal tumor patients. World J Gastrointest Oncol 2025; 17(5): 102647 [DOI: 10.4251/wjgo.v17.i5.102647]
Corresponding Author of This Article
Dan-Ye Niu, PhD, Associate Chief Physician, Department of Clinical Nutrition, Suzhou Municipal Hospital, Gusu School, Nanjing Medical University, No. 16 Baita West Road, Gusu District, Suzhou 215000, Jiangsu Province, China. niu12748249@126.com
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Retrospective Study
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Shuai Zhang, Wan-Ci Li, Department of Interventional, The First Affiliated Hospital of Soochow University, Suzhou 215000, Jiangsu Province, China
Jiao Liu, Yu Tang, Dan-Ye Niu, Department of Clinical Nutrition, Suzhou Municipal Hospital, Gusu School, Nanjing Medical University, Suzhou 215000, Jiangsu Province, China
Co-first authors: Shuai Zhang and Wan-Ci Li.
Author contributions: Zhang S and Li WC are jointly responsible for data collection and design research, and contributed equally to this work as co-first authors; Liu J, Tang Y, and Niu DY contributed to the analysis of the manuscript; Zhang S, Li WC and Niu DY were involved in the data and writing of this article; and all authors have read and approved the final manuscript.
Institutional review board statement: This study was reviewed and approved by the Institutional Review Board of The First Affiliated Hospital of Soochow University (No. KL901547).
Informed consent statement: All study participants, or their legal guardian, provided informed written consent prior to study enrollment.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Data sharing statement: No additional data are available.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Dan-Ye Niu, PhD, Associate Chief Physician, Department of Clinical Nutrition, Suzhou Municipal Hospital, Gusu School, Nanjing Medical University, No. 16 Baita West Road, Gusu District, Suzhou 215000, Jiangsu Province, China. niu12748249@126.com
Received: January 10, 2025 Revised: February 18, 2025 Accepted: March 18, 2025 Published online: May 15, 2025 Processing time: 124 Days and 17.9 Hours
Abstract
BACKGROUND
Malnutrition exacerbates the deterioration in patients with advanced gastrointestinal tumors.
AIM
To analyze the effect of enteral nutritional support based on Nutrition Risk Screening 2002 (NRS2002) risk assessment on nutritional function in patients with gastrointestinal tumors.
METHODS
One hundred twelve patients from April 2022 to April 2024 were included for observation and were divided into a control group and an observation group by random number method, 56 each. Both groups received treatment for four consecutive weeks. The control group received routine enteral nutrition support, while the observation group received enteral nutrition support based on the NRS2002 risk assessment. Nutritional function, intestinal mucosal barrier function, quality of life, and complication rate were compared between the two groups. Statistical analysis was completed using SPSS26.0 and Excel.
RESULTS
After nutritional intervention, transferrin, albumin, hemoglobin, and diamine oxidase levels in the observation group were higher than those in the control group, while C-reactive protein, tumor necrosis factor α, and quality of life scores were lower, with significant differences (P < 0.05). There was no significant difference in complications between groups (P > 0.05), but the complication rate was lower in the observation group.
CONCLUSION
Enteral nutritional support based on NRS2002 risk assessment for patients with gastrointestinal tumors positively impacts nutritional status and promotes intestinal mucosal barrier function recovery. Patients’ quality of life improved, and the incidence of adverse reactions decreased, indicating clinical promotion and application value.
Core Tip: Effective enteral nutrition support holds utmost significance for tumor patients. In particular, those diagnosed with gastrointestinal tumors often face challenges like malabsorption due to their condition. Adequate enteral nutrition not only provides essential nutrients to maintain strength but also helps boost the immune system, enabling patients to better endure cancer treatments such as chemotherapy and radiotherapy.
