Yin JJ, Hu X, Hu S, Sheng GH. Efficacy of multi-slice spiral computed tomography in evaluating gastric cancer recurrence after endoscopic submucosal dissection. World J Gastrointest Oncol 2023; 15(9): 1636-1643 [PMID: 37746651 DOI: 10.4251/wjgo.v15.i9.1636]
Corresponding Author of This Article
Xiao Hu, RN, Associate Chief Nurse, Department of Geriatrics, Huangshi Central Hospital, Affiliated Hospital of Hubei Polytechnic University, No. 19 Floor, Building 6, Huangshi 435000, Hubei Province, China. 11786356@qq.com
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Retrospective Study
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Gastrointest Oncol. Sep 15, 2023; 15(9): 1636-1643 Published online Sep 15, 2023. doi: 10.4251/wjgo.v15.i9.1636
Efficacy of multi-slice spiral computed tomography in evaluating gastric cancer recurrence after endoscopic submucosal dissection
Jian-Jun Yin, Xiao Hu, Sen Hu, Guo-Hong Sheng
Jian-Jun Yin, Sen Hu, Guo-Hong Sheng, Department of Radiology, Huangshi Maternity and Children's health Hospital, Affiliated Maternity and Children's Health Hospital of Hubei Polytechnic University, Huangshi 435000, Hubei Province, China
Xiao Hu, Department of Geriatrics, Huangshi Central Hospital, Affiliated Hospital of Hubei Polytechnic University, Huangshi 435000, Hubei Province, China
Author contributions: Yin JJ and Hu X contributed equally to this work; Hu S designed the study; Sheng GH contributed to the analysis of the manuscript; Yin JJ and Hu X were involved in the data and writing of this article; and all authors have read and approved the final manuscript.
Institutional review board statement: The study was reviewed and approved by the Huangshi Maternity and Children's health Hospital, Affiliated Maternity and Children's health Hospital of Hubei Polytechnic University, Huangshi, China, Institutional Review Board.
Informed consent statement: All study participants and their legal guardians provide informed written consent before the study recruitment.
Conflict-of-interest statement: All authors have no conflicts of interest.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Xiao Hu, RN, Associate Chief Nurse, Department of Geriatrics, Huangshi Central Hospital, Affiliated Hospital of Hubei Polytechnic University, No. 19 Floor, Building 6, Huangshi 435000, Hubei Province, China. 11786356@qq.com
Received: July 4, 2023 Peer-review started: July 4, 2023 First decision: July 19, 2023 Revised: July 25, 2023 Accepted: August 8, 2023 Article in press: August 8, 2023 Published online: September 15, 2023
Abstract
BACKGROUND
Recurrence is the major challenge facing endoscopic submucosal dissection (ESD)-based treatment therapies for early gastric cancer (EGC). Urgent development of simple and easy surveillance approaches will enhance clinical treatment of the disease.
AIM
To explore the role of computed tomography (CT) recurrence in evaluating EGC after ESD treatment.
METHODS
We retrospectively recruited patients from our endoscopy department, between January 2002 and December 2015, and analyzed their basic characteristics, including symptoms, CT results, and results of endoscopy with biopsy, among others.
RESULTS
Among a total of 2150 patients EGC patients surveyed, 1362 met our inclusion and exclusion criteria and were therefore enrolled in our study. The cohort’s sensitivity of CT for recurrent GC and specificity were 44.22% and 43.86%, respectively, with negative and positive predictive values of 40.15% (275/685) and 48.01% (325/677), respectively. The area under the curve of arterial and venous CT values for recurrent EGC were 0.545, and 0.604, respectively. Receiver operating characteristic curve revealed no statistically significant differences between arterial and venous CT values for recurrent EGC.
CONCLUSION
Enhanced CT has superior diagnostic efficacy, but less accuracy, compared to gold standard techniques in patients with recurrent EGC.
Core Tip: Development of a simple and easy approach to detect recurrence of early gastric cancer (EGC) treated with endoscopic mucosal exfoliation is imperative to effective clinical therapy. Here, we report the feasibility of multi-slice spiral computed tomography (CT), a quick and convenient auxiliary examination with sensitivity and specificity values of 44.22% and 43.86%, respectively, in evaluating arterial and venous CT values for recurrent EGC. Area under the curve value of arterial and venous CT values for recurrent EGC respectively were 0.55 and 0.60, indicating that enhanced CT can accurately predict EGC, although with low accuracy.
