Clipping prevents perforation in large, flat polyps

Table 1 Patient and procedure data for Phases 1 and 2 n (%)

	Phase 1(n = 55)	Phase 2(n = 116)
Indications for colonoscopy1
Surveillance	38 (69)	85 (73)
Screening	12 (21.8)	29 (25)
Abdominal pain/diarrhea	8 (14.5)	11 (9.5)
Bleeding	6 (10.9)	7 (6)
Change in bowel habits	2 (3.6)	2 (1.7)
Evaluation/therapy of known lesions	1 (1.8)	2 (1.7)
Anemia	3 (5.5)	2 (1.7)
Abnormal imaging	N/A	2 (1.7)
Other	1 (1.8): Diverticulitis	3 (2.6): Diverticulitis: 1 Rectal prolapse: 1 Rectal pain: 1
Patient characteristics
Male/female (n)	36/19	65/51
Mean age (Range)	69.3 (37-87)	65.5 (29-87)
Family history of colon cancer	12 (21.8)	27 (23.3)
Procedure data and outcomes
Total colonoscopies	2121	2464
Total polyps	65	151
Polyp size (cm): (Mean ± SD, median, range)	2 ± 0.69, 2, 1.2-4	1.81 ± 0.54, 1.6, 1.2-4
Clips/polyp (Mean ± SD, median)	N/A	2.17 + 0.97, 2
Polypectomy duration (min): Mean (SD), median, range	18.69 (15.31), 18, 2-61	16.4 (10.04), 13, 4-592
Procedure duration (min): Mean (SD), median, range	44.70 (18.83), 41, 14-97	42.90 (15.60), 40, 20-96
Prevalence of large, flat right- sided polyps	3.8% (81/2121 procedures)	6.3% (154/2464 procedures)
Complications	Post-polypectomy bleeds: 0 Perforations: 2 3.6% of patients, 3% of polypectomies	Post-polypectomy bleeds: 0 Perforations: 0

¹Total indications exceeds number of patients due to patients having multiple indications;

²Three polypectomies excluded due to incomplete data. N/A: Not available.

Table 2 Polyp histopathology n (%)

	Phase 11 (n = 65)	Phase 2 (n = 151)
Sessile serrated adenoma	16 (25.0)	68 (45.0)
Tubular adenoma	31 (48.0)	47 (31.0)
Hyperplastic	10 (15.0)	24 (16.0)
Tubulovillous	7 (11.0)	7 (5.0)
Normal	1 (1.5)	2 (1.3)
Fibroepithelial	1 (1.5)	N/A
Lipoma	N/A	2 (1.3)
Pneumatosis coli	N/A	1 (0.7)

¹Phase 1 total exceeds sample size due to 1 mixed polyp. N/A: Not available.