Clinical relevance of aberrant polypoid nodule scar after endoscopic submucosal dissection

Table 1 Endoscopic submucosal dissection procedures distribution in Centers 1 and 2 and incidence of polypoid nodule scar according to region of the stomach n (%)

ESD procedures	Center 1 (Brazil)	Center 2 (Japan)
Total number of gastric ESD (n)	60	343
ESD in antrum	37 (62%)	158 (46%)
ESD in proximal stomach	23 (36%)	185 (54%)
Total number of PNS cases	8 (13.3%)	6 (1.7%)
Number of PNS in antrum lesions	8 (21.6%)	6 (3.8%)
Number of PNS in proximal stomach	0 (0%)	0 (0%)

ESD: Endoscopic submucosal dissection; PNS: Polypoid nodule scar.

Table 2 Characteristics of tumors and follow-up data

Case list	Gastric region	Location	Tumor size (mm)	H. pylori status before ESD	Specimen size (mm)	Histology	Tumor depth	Post-ESD treatment	Follow-up (yr)
1	Antrum	Anterior wall	8	Positive	30	Moderately differentiated adenocarcinoma	M	Rabeprazole	8
2	Antrum	Greater curvature	13	Positive	37	Well differentiated adenocarcinoma	M	Omeprazole	11
3	Antrum	Lesser curvature	25	Positive	50	Well differentiated adenocarcinoma	M	Rabeprazole	13
4	Antrum	Greater curvature	15	Positive	32	Well differentiated adenocarcinoma	M	Rabeprazole	5
5	Antrum	Lesser curvature	8	Negative	20	Well differentiated adenocarcinoma	M	Rabeprazole	2
6	Antrum	Greater curvature	10	Negative	20	High-grade dysplasia	M	Omeprazole	7
7	Antrum	Lesser curvature	25	Positive	40	Well differentiated adenocarcinoma	M	Omeprazole + sucralfate	4
8	Antrum	Greater curvature	20	Positive	40	High-grade dysplasia	M	Esomeprazole + sucralfate	4
9	Antrum	Anterior wall	12	Positive	22	High-grade dysplasia	M	Omeprazole + sucralfate	4
10	Antrum	Greater curvature	25	Negative	40	Inflammatory lesion indefinite for dysplasia	M	Esomeprazole + sucralfate	4
11	Antrum	Anterior wall	20	Negative	35	Inflammatory fibroid polyp	SM	Omeprazole + sucralfate	2
12	Antrum	Greater curvature	30	Positive	40	High-grade dysplasia	M	Omeprazole + sucralfate	1
13	Angle	Lesser curvature	45	Negative	82	Well differentiated adenocarcinoma	M	Rabeprazole	2
14	Antrum	Posterior wall	20	Negative	32	High-grade dysplasia	M	Omeprazole + sucralfate	1

ESD: Endoscopic submucosal dissection; H. pylori: Helicobacter pylori; M: Mucosa; SM: Submucosa.