Copyright
©The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Endosc. Sep 16, 2016; 8(17): 628-634
Published online Sep 16, 2016. doi: 10.4253/wjge.v8.i17.628
Published online Sep 16, 2016. doi: 10.4253/wjge.v8.i17.628
Clinical relevance of aberrant polypoid nodule scar after endoscopic submucosal dissection
Vitor Arantes, Endoscopy Unit, Alfa Institute of Gastroenterology, School of Medicine, Federal University of Minas Gerais, Hospital Mater Dei Contorno, Belo Horizonte 30130-100, Brazil
Noriya Uedo, Department of Gastrointestinal Oncology, Osaka Medical Center for Cancer and Cardiovascular Diseases, Osaka 537-8511, Japan
Moises Salgado Pedrosa, Laboratory CEAP, Department of Pathology, School of Medicine, Federal University of Minas Gerais, Belo Horizonte 30130-090, Brazil
Yasuhiko Tomita, Department of Pathology, Osaka Medical Center for Cancer and Cardiovascular Diseases, Osaka 537-8511, Japan
Author contributions: Arantes V and Uedo N designed the study and contributed equally to data acquisition, analysis, interpretation of the data, writing the article, critical revision and final approval of the manuscript; Pedrosa MS and Tomita Y contributed equally to the histopathological analysis and interpretation of histological findings and study results.
Institutional review board statement: The data was extracted retrospectively from the endoscopy database. Our Ethics and Research Committee does not require IRB submission for such kind of study. Patients signed a consent form for the procedure and the study was conducted according to Helsinque Declaration.
Informed consent statement: All study participants, or their legal guardian, provided informed written consent prior to study enrollment.
Conflict-of-interest statement: There are no conflicts of interest to report.
Data sharing statement: No data were created so no data are available.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Vitor Arantes, MD, MSc, PhD, Endoscopy Unit, Alfa Institute of Gastroenterology, School of Medicine, Federal University of Minas Gerais, Hospital Mater Dei Contorno, Rua Florália 18, apt. 1201, Anchieta, Belo Horizonte 30130-100, Brazil. arantesvitor@ufmg.br
Telephone: +55-319-96173441
Received: March 21, 2016
Peer-review started: March 23, 2016
First decision: April 20, 2016
Revised: April 26, 2016
Accepted: July 11, 2016
Article in press: July 13, 2016
Published online: September 16, 2016
Peer-review started: March 23, 2016
First decision: April 20, 2016
Revised: April 26, 2016
Accepted: July 11, 2016
Article in press: July 13, 2016
Published online: September 16, 2016
Core Tip
Core tip: Endoscopic submucosal dissection is the treatment of choice for superficial gastric neoplasms. After curative endoscopic submucosal dissection (ESD), postoperative scar is expected to look consolidated and homogeneous. We describe a series of 14 patients that underwent curative gastric ESD with R0 resection and surprisingly developed an aberrant polypoid nodule at the ESD scar. We denominated this new entity as polypoid nodule scar (PNS). It is noteworthy that PNS occurred only after ESD undertaken for tumors located in the antrum. We reviewed the hypothesis and pathogenic factors that could explain the occurrence of this unusual phenomenon, and discuss propositions about patient’s postoperative clinical management.