Case Report
Copyright ©2014 Baishideng Publishing Group Co.
World J Gastrointest Endosc. Jan 16, 2014; 6(1): 27-31
Published online Jan 16, 2014. doi: 10.4253/wjge.v6.i1.27
Table 1 Results of clinical laboratory tests and examinations
Clinical examinationsResults
Routine blood examinationWhite blood cells 14400/μL, red blood cells 408 × 104/μL, hemoglobin 11.6 g/dL, hematocrit 35.7%, platelets 220 × 104/μL, C-reactive protein 38.9 mg/dL, blood sedimentation 58 mm/h
Routine stool examinationWhite blood cells, 20-30/HP; red blood cells, filled visual fields
Blood biochemistryTotal protein, 8.6 g/dL; AST, 36 IU/L; ALT, 32 IU/L; LDH, 171 IU/L; and total bilirubin, 0.2 mg/dL
Bacteriologic culture of blood, urine, and stoolNegative
Serum antinuclear antibody and antituberculosis antibodyNegative
PPD skin test and T-spot testNegative
Pathergy testPositive
GastroscopyGiant ulceration in the inferior extremity of the esophagus (Figure 1A)
ColonoscopyA large ulcer in the ileo-cecal junction (Figure 1B)
Pathological examination of the endoscopic biopsy specimenNonspecific ulceration
Abdominal CT imagingThickening of the intestinal canal of the ascending colon and ileocecal region
Whole gastrointestinal barium meal examinationInflammatory changes in the ascending colon and ileocecal region
Table 2 Diagnostic Criteria (Behcet’s Disease Resarch Committee of Japan, 1987)
Recurrent aphthous ulceration of the oral mucous membrane
Skin lesion
Erythema nodosum
Subcutaneous thrombophlebitis
Folliculitis, acne-like lesion
Cutaneous hyperirritability
Eye lesion
Chorioretinitis, retinouveitis
Definite history of chorioretinitis of retinouveitis
Genital ulcer
Arthritis without deformity and ankylosis
Gastrointestinal lesion characterized by ileocecal ulcers
Vascular lesion
Central nervous system symptoms
Complete type:4 major features
Incomplete type:
3 major features
Major + 2 minor features
Typical ocular symptom + 1 major or 2 minor features
Suspected type:
2 major features
1 major + 2 minor
Table 3 Guideline Statements for Diagnosis of Intestinal Behcet’s Disease (Japan)
Diagnosis of intestinal Behcet’s disease can be made if
There is a typical oval-shaped large ulcer in the terminal ileum or
There are ulcerations or inflammation in the small or large intestine;
And clinical findings meet the diagnostic criteria of Behcet’s disease