Histological diagnosis of gastric submucosal tumors: A pilot study of endoscopic ultrasonography-guided fine-needle aspiration biopsy vs mucosal cutting biopsy

Table 2 Diagnostic yields obtained with endoscopic ultrasonography-guided fine-needle aspiration biopsy and mucosal cutting biopsy

	EUS-FNAB				P value	MCB				P value
	Diagnosed (%)(n = 13)		Not diagnosed (%)(n = 7)			Diagnosed (%)(n = 12)		Not diagnosed (%)(n = 8)
Histological diagnosis	13 (65.0)					12 (60.0)				> 0.99
Location 1
Upper	7	(63.6)	4	(36.4)	0.33	8	(72.7)	3	(27.3)	0.28
Middle	6	(75.0)	2	(25.0)		4	(50.0)	4	(50.0)
Lower	0	(0)	1	(100)		0	(0)	1	(100)
Location 2
Lesser curvature	4	(66.7)	2	(33.3)	0.81	3	(50.0)	3	(50.0)	0.27
Greater curvature	2	(50.0)	2	(50.0)		1	(25.0)	3	(75.0)
Anterior wall	4	(80.0)	1	(20.0)		4	(80.0)	1	(20.0)
Posterior wall	3	(60.0)	2	(40.0)		4	(80.0)	1	(20.0)
Tumor size
≤ 20 mm	7	(58.3)a	5	(41.7)	0.641	9	(75.0)a	3	(25.0)	0.171
> 20 mm	6	(75.0)c	2	(25.0)		3	(37.5)c	5	(62.5)
Growth pattern
Intraluminal	9	(56.3)e	7	(43.8)	0.101	12	(75.0)e	4	(25.0)	0.011
Extraluminal	4	(100)b	0	(0)		0	(0)b	4	(100)
Median number of samples to the diagnosis (IQR)	1.0	(1.0, 1.0)				1.0	(1.0, 1.75)
Median number of samples (IQR)	3.0	(2.5, 3.5)	3.0	(3.0, 3.0)	0.93	5.0	(3.0, 6.0)	2.5	(1.0, 5.75)	0.17

¹P values were calculated using Fisher’s exact test;

^aP = 0.67 between EUS-FNAB and MCB in tumor size ≤ 20 mm; Fisher’s exact test;

^cP = 0.31 between EUS-FNAB and MCB in tumor size > 20 mm; Fisher’s exact test;

^eP = 0.46 between EUS-FNAB and MCB in intraluminal growth pattern; Fisher’s exact test;

^bP = 0.03 between EUS-FNAB and MCB in extraluminal growth pattern. EUS-FNAB: Endoscopic ultrasonography-guided fine-needle aspiration biopsy; IQR: Interquartile range; MCB: Mucosal cutting biopsy.