Doradla P, Joseph C, Giles RH. Terahertz endoscopic imaging for colorectal cancer detection: Current status and future perspectives. World J Gastrointest Endosc 2017; 9(8): 346-358 [PMID: 28874955 DOI: 10.4253/wjge.v9.i8.346]
Corresponding Author of This Article
Pallavi Doradla, PhD, Wellman Center for Photomedicine, Harvard Medical School, 55 Fruit Street, Boston, MA 02114, United States. pdoradla@mgh.harvard.edu
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Review
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Gastrointest Endosc. Aug 16, 2017; 9(8): 346-358 Published online Aug 16, 2017. doi: 10.4253/wjge.v9.i8.346
Terahertz endoscopic imaging for colorectal cancer detection: Current status and future perspectives
Pallavi Doradla, Cecil Joseph, Robert H Giles
Pallavi Doradla, Wellman Center for Photomedicine, Harvard Medical School, Boston, MA 02114, United States
Pallavi Doradla, Cecil Joseph, Robert H Giles, Biomedical Terahertz Technology center, Department of Physics, University of Massachusetts Lowell, Lowell, MA 01854, United States
Author contributions: Doradla P performed the research work, analyzed the collected data, conducted the literature review, and wrote the manuscript; Joseph C contributed to the review of the literature and revised the draft; Giles RH supervised the review.
Conflict-of-interest statement: Authors declare no conflicts of interests for this article.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Pallavi Doradla, PhD, Wellman Center for Photomedicine, Harvard Medical School, 55 Fruit Street, Boston, MA 02114, United States. pdoradla@mgh.harvard.edu
Telephone: +1-617-7263417 Fax: +1-617-6439208
Received: December 31, 2016 Peer-review started: January 5, 2017 First decision: February 21, 2017 Revised: June 8, 2017 Accepted: July 14, 2017 Article in press: July 15, 2017 Published online: August 16, 2017
Core Tip
Core tip: Terahertz (THz) imaging is progressing as a robust platform for a myriad of applications in the field of medicine. The non-ionizing THz radiation associated with safe energy levels has the potential to achieve high-resolution images of an organ or tissue, effectively combining both macroscopic and microscopic information. THz reflection imaging provides an intrinsic contrast between normal and diseased tissues, in real-time. This review describes the design, development, and practical implication of flexible THz endoscopic system, while simultaneously obtaining an overview of the existing technology. In addition to the state-of-art THz endoscopy, the feasibility study of a single-channel THz endoscopic system for colorectal cancer screening will be highlighted.
