Retrospective Study
Copyright ©The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Endosc. Jul 16, 2017; 9(7): 310-318
Published online Jul 16, 2017. doi: 10.4253/wjge.v9.i7.310
Use of shape-from-shading to characterize mucosal topography in celiac disease videocapsule images
Edward J Ciaccio, Govind Bhagat, Suzanne K Lewis, Peter H Green
Edward J Ciaccio, Govind Bhagat, Suzanne K Lewis, Peter H Green, Department of Medicine, Celiac Disease Center, Columbia University, New York, NY 10032, United States
Govind Bhagat, Department of Pathology and Cell Biology, Columbia University Medical Center, New York, NY 10032, United States
Author contributions: All the authors contributed to this manuscript.
Institutional review board statement: The study protocol has been approved by the Columbia University Medical Center IRB.
Conflict-of-interest statement: The authors have no conflicts of interest.
Data sharing statement: None.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Edward J Ciaccio, PhD, Department of Medicine, Celiac Disease Center, Columbia University, Harkness Pavilion 804, 180 Fort Washington Avenue, New York, NY 10032, United States. ciaccio@columbia.edu
Telephone: +1-212-3055447 Fax: +1-212-3420447
Received: December 14, 2016
Peer-review started: December 16, 2016
First decision: January 14, 2017
Revised: March 8, 2017
Accepted: June 6, 2017
Article in press: June 8, 2017
Published online: July 16, 2017
Core Tip

Core tip: Videocapsule images can assist in determining the presence and status of celiac disease; however, pathology is not always apparent by visual inspection. A computerized shape-from-shading technique was used to characterize the topography of the small intestinal mucosa. It was hypothesized that the automated measure would be helpful to distinguish celiac from control images and to gauge the degree of villous atrophy in the celiac patient data.