Systematic Reviews
Copyright ©The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Endosc. Jul 25, 2016; 8(14): 489-495
Published online Jul 25, 2016. doi: 10.4253/wjge.v8.i14.489
Endoscopic full thickness resection for gastric tumors originating from muscularis propria
Deepanshu Jain, Ejaz Mahmood, Aakash Desai, Shashideep Singhal
Deepanshu Jain, Ejaz Mahmood, Department of Internal Medicine, Albert Einstein Medical Center, Philadelphia, PA 19141, United States
Aakash Desai, Shashideep Singhal, Division of Gastroenterology, Hepatology and Nutrition, University of Texas Health Science Center at Houston, Houston, TX 77030, United States
Author contributions: Jain D contributed to literature review, interpretation of data and drafting of the manuscript; Mahmood E contributed in acquisition of data, interpretation of data and drafting of the manuscript; Desai A contributed in acquisition of data; Singhal S contributed to literature review and critical revision of the manuscript for important intellectual content.
Conflict-of-interest statement: None of the authors have any conflicts of interest.
Data sharing statement: Our article is a systematic review and thus it does not apply to our article.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Shashideep Singhal, MD, Division of Gastroenterology, Hepatology and Nutrition, University of Texas Health Science Center at Houston, 6431 Fannin, MSB 4.234, Houston, TX 77030, United States. sdsinghal@gmail.com
Telephone: +1-713-5006677 Fax: +1-713-5006699
Received: March 6, 2016
Peer-review started: March 7, 2016
First decision: April 6, 2016
Revised: May 6, 2016
Accepted: May 31, 2016
Article in press: June 2, 2016
Published online: July 25, 2016
Core Tip

Core tip: Endoscopic submucosal dissection success for gastric submucosal tumors arising from muscularis propria has remained limited. Authors have reported success with endoscopic full thickness resection (EFTR) in achieving complete resection of gastric tumors (as large as 5 cm) originating from musucularis propria in the absence of major complications. EFTR seems to be a reasonable replacement for laparoscopic technique for this subset of patients. Careful selection of candidates by preoperative imaging and endoscopy including endoscopic ultrasound to rule out metastatic disease and to confirm the size and location of lesion remains crucial.