Review
Copyright ©The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Endosc. Jul 25, 2015; 7(9): 872-880
Published online Jul 25, 2015. doi: 10.4253/wjge.v7.i9.872
Recent development of optical coherence tomography for preoperative diagnosis of esophageal malignancies
Kaname Uno, Tomoyuki Koike, Tooru Shimosegawa
Kaname Uno, Tomoyuki Koike, Tooru Shimosegawa, Division of Gastroenterology, Tohoku University Hospital, Miyagi 981-8574, Japan
Author contributions: All authors contributed to this paper.
Conflict-of-interest statement: None.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Kaname Uno, MD, PhD, Division of Gastroenterology, Tohoku University Hospital, 1-1 Seiryo-cho, Aoba-ku, Sendai, Miyagi 981-8574, Japan. kaname@wa2.so-net.ne.jp
Telephone: +81-22-7177171 Fax: +81-22-7177174
Received: April 22, 2015
Peer-review started: April 30, 2015
First decision: May 13, 2015
Revised: May 20, 2015
Accepted: June 15, 2015
Article in press: June 16, 2015
Published online: July 25, 2015
Core Tip

Core tip: Optical coherence tomography (OCT) provides real-time cross-sectional images with extremely high resolution. We previously reported that OCT provided significantly more accurate preoperative staging of esophageal squamous carcinoma (ESCC) than endosonography. With remarkable improvements in this technology, such as three-dimensional devices with Doppler capability, for the detection of Barrett’s-associated neoplasia, the diagnostic accuracy gradually became better through enhanced visualization of structural/functional alterations in mucosal/submucosal tissue. Recent reports suggested its usefulness for targeting malignant lesions for endoscopic intervention and for predicting treatment effects. Therefore, further development of OCT should promote improved management strategies for esophageal malignancies, including ESCC.