Copyright
©The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Endosc. Jun 25, 2015; 7(7): 736-740
Published online Jun 25, 2015. doi: 10.4253/wjge.v7.i7.736
Published online Jun 25, 2015. doi: 10.4253/wjge.v7.i7.736
Obtaining research biopsies during pediatric colonoscopy: Safety and adverse events
Jennifer Mait-Kaufman, Gitit Tomer, Department of Pediatric Gastroenterology and Nutrition, Albert Einstein College of Medicine, Children’s Hospital at Montefiore, Bronx, NY 10467, United States
Stacie Kahn, Albert Einstein College of Medicine, Bronx, NY 10467, United States
Author contributions: All authors contributed to this manuscript.
Ethics approval: This study was approved by the Office of the Human Research Protection Program, Institutional Review Board at Albert Einstein College of Medicine, Bronx, NY.
Informed consent: All study participants, or their legal guardian, provided informed written consent prior to study enrollment.
Conflict-of-interest: None of the authors have a conflict of interest.
Data sharing: Consent for data sharing was not obtained. All data was collected in a de-identified and anonymous manner.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Jennifer Mait-Kaufman, MD, Department of Pediatric Gastroenterology and Nutrition, Albert Einstein College of Medicine, Children’s Hospital at Montefiore, 3415 Bainbridge Avenue, Rosenthal 3, Bronx, NY 10467, United States. jmait@montefiore.org
Received: December 19, 2014
Peer-review started: December 22, 2014
First decision: January 8, 2015
Revised: January 22, 2015
Accepted: March 4, 2015
Article in press: March 6, 2015
Published online: June 25, 2015
Peer-review started: December 22, 2014
First decision: January 8, 2015
Revised: January 22, 2015
Accepted: March 4, 2015
Article in press: March 6, 2015
Published online: June 25, 2015
Core Tip
Core tip: Acquiring biopsies for research purposes during a colonoscopy may facilitate translational research in the field of gastroenterology. However, the safety profile of acquiring research biopsies has not been established. Our study is the first to conclude that acquiring additional biopsies for research during a colonoscopy does not pose additional risk to the pediatric patient. This manuscript may serve as a reference to researchers applying for IRB approval in biological specimen studies. Additionally, our study is additive to the body of literature on outcomes after pediatric colonoscopy, in that minor gastrointestinal symptoms were the only reported adverse event after colonoscopy.