Copyright ©The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Endosc. Jun 25, 2015; 7(7): 720-727
Published online Jun 25, 2015. doi: 10.4253/wjge.v7.i7.720
Endoscopic mucosal resection and endoscopic submucosal dissection in the treatment of sporadic nonampullary duodenal adenomatous polyps
Joana Marques, Francisco Baldaque-Silva, Pedro Pereira, Urban Arnelo, Naohisa Yahagi, Guilherme Macedo
Joana Marques, Faculty of Medicine, University of Porto, 4200 Porto, Portgal
Francisco Baldaque-Silva, Gastrocentrum Karolinska University Hospital, Karolinska Institutet, S-14186 Stockholm, Sweden
Pedro Pereira, Guilherme Macedo, Gastroenterology Department, Hospital São João, 4200 Porto, Portugal
Urban Arnelo, Division of Surgery, Department of Clinical Science, Intervention and Technology (CLINTEC), Karolinska Institutet, and Centre for Digestive Diseases, Karolinska University Hospital, S-14186 Stockholm, Sweden
Naohisa Yahagi, Division of Research and Development for Minimally Invasive Treatment, Cancer Center, School of Medicine, Keio University, Shinjuku-ku, Tokyo 160-8582, Japan
Author contributions: All the authors contributed to this manuscript.
Conflict-of-interest: The authors declare no conflict of interests related to this paper.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See:
Correspondence to: Francisco Baldaque-Silva, MD, Gastrocentrum Karolinska University Hospital, Karolinska Institutet, Karolinska vägen, S-14186 Stockholm, Sweden.
Telephone: +46-08-58586902 Fax: +46-08-58582489
Received: October 29, 2014
Peer-review started: November 2, 2014
First decision: December 12, 2014
Revised: April 16, 2015
Accepted: May 16, 2015
Article in press: May 18, 2015
Published online: June 25, 2015
Core Tip

Core tip: Widespread use of endoscopy leads to increase detection of sporadic nonampullary duodenal adenomas. Due to significant morbidity and mortality of surgical treatment in this setting, endoscopic treatment with endoscopic mucosal resection (EMR) or endoscopic submucosal dissection (ESD), has been progressively used for the resection of these lesions. This extensive and detailed review discusses the efficacy and safety of EMR and ESD in this context. We conclude that EMR and ESD are valid options for the treatment of sporadic nonampullary duodenal adenomas. Strategies to improve these techniques, and consequently increase their effectiveness and safety should be developed.