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©The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Endosc. May 16, 2015; 7(5): 547-554
Published online May 16, 2015. doi: 10.4253/wjge.v7.i5.547
Published online May 16, 2015. doi: 10.4253/wjge.v7.i5.547
Biliary leakage after urgent cholecystectomy: Optimization of endoscopic treatment
Neven Ljubičić, Alen Bišćanin, Tajana Pavić, Marko Nikolić, Ivan Budimir, Ana Đuzel, Division of Gastroenterology, Department of Internal Medicine, “Sestre milosrdnice” University Hospital, Zagreb 10000, Croatia
August Mijić, Division of Hepato-biliary Surgery, Department of Surgery, “Sestre milosrdnice” University Hospital, Zagreb 10000, Croatia
Author contributions: Ljubičić N, Bišćanin A and Mijić A contributed to study conception and design; Ljubičić N, Bišćanin A, Pavić T, Nikolić M, Budimir I, Mijić A and Đuzel A performed the research; Ljubičić N, Bišćanin A and Đuzel A analyzed the data; Ljubičić N and Bišćanin A wrote the paper.
Ethics approval: The study was approved by the “Sestre milosrdnice” University Hospital Review Board (EP-13127/08-15).
Informed consent: All study participants, or their legal guardian, provided informed written consent prior to study enrollment.
Conflict-of-interest: The authors have no conflicts of interest or financial ties to disclose.
Data sharing: No additional data are available.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Neven Ljubičić, MD, PhD, FACG, Professor, Division of Gastroenterology, Department of Internal Medicine, “Sestre milosrdnice” University Hospital, Vinogradska cesta 29, Zagreb 10000, Croatia. neven.ljubicic@kbcsm.hr
Telephone: +385-1-3768286 Fax: +385-1-3768286
Received: November 22, 2014
Peer-review started: November 22, 2014
First decision: December 12, 2014
Revised: February 12, 2015
Accepted: March 5, 2015
Article in press: March 9, 2015
Published online: May 16, 2015
Peer-review started: November 22, 2014
First decision: December 12, 2014
Revised: February 12, 2015
Accepted: March 5, 2015
Article in press: March 9, 2015
Published online: May 16, 2015
Core Tip
Core tip: Biliary leakage can be a serious complication of urgent cholecystectomy even in the hands of an experienced surgeon. Endoscopic interventions replaced surgery as first-line treatment for most of the biliary ducts injuries and biliary leakage after cholecystectomy. Long-term follow-up results demonstrate the great efficiency of the endoscopic therapy in the treatment of the patients with biliary leakage after urgent cholecystectomy. Early cessation of bile output from the external abdominal drain strongly indicates healing of the leak and in those patients repeat cholangiography is not necessary, particularly if the presenting symptoms and/or signs of the biliary leakage disappeared.