Copyright
©The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Endosc. Dec 10, 2015; 7(18): 1262-1267
Published online Dec 10, 2015. doi: 10.4253/wjge.v7.i18.1262
Published online Dec 10, 2015. doi: 10.4253/wjge.v7.i18.1262
Opinion: How to manage subepithelial lesions of the upper gastrointestinal tract?
Matheus Cavalcante Franco, Ricardo Teles Schulz, Fauze Maluf-Filho, Digestive Endoscopy Unit, Cancer Institute of São Paulo University, São Paulo 05612-000, Brazil
Author contributions: Franco MC, Schulz RT and Maluf-Filho F performed the research, wrote the article, and did a critical revision of the article for important intellectual content.
Conflict-of-interest statement: The authors have no conflict of interests.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Fauze Maluf-Filho, MD, PhD, Director, Digestive Endoscopy Unit, Cancer Institute of São Paulo University, R. Olegario Mariano, 488, São Paulo 05612-000, Brazil. fauze.maluf@terra.com.br
Telephone: +55-11-38847599 Fax: +55-11-38932296
Received: May 28, 2015
Peer-review started: May 28, 2015
First decision: August 25, 2015
Revised: September 28, 2015
Accepted: November 10, 2015
Article in press: November 11, 2015
Published online: December 10, 2015
Peer-review started: May 28, 2015
First decision: August 25, 2015
Revised: September 28, 2015
Accepted: November 10, 2015
Article in press: November 11, 2015
Published online: December 10, 2015
Core Tip
Core tip: Subepithelial lesions (SELs) of the upper gastrointestinal tract include a broader differential diagnosis, which can range from non-malignant tumors to lesions with malignant potential such as gastrointestinal stromal tumors. The possibility of having a potentially malignant lesion may bring anxiety and discomfort to patients and doctors. Further investigation should be carried out for patients with high-risk lesions after risk stratification. This editorial presents the current evidence about the diagnostic management of SELs.