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©2014 Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Endosc. Jul 16, 2014; 6(7): 318-323
Published online Jul 16, 2014. doi: 10.4253/wjge.v6.i7.318
Published online Jul 16, 2014. doi: 10.4253/wjge.v6.i7.318
Conservative approach in Peutz-Jeghers syndrome: Single-balloon enteroscopy and small bowel polypectomy
Filippo Torroni, Erminia Romeo, Francesca Rea, Paola De Angelis, Francesca Foschia, Simona Faraci, Giovanni Federici di Abriola, Anna Chiara Contini, Tamara Caldaro, Luigi Dall’Oglio, Department of Surgery and Transplantation, Digestive Surgery and Endoscopy Unit, Bambino Gesù Children’s Hospital, IRCCS, 00165 Rome, Italy
Author contributions: Torroni F and Rea F contributed to the manuscript writing and scientific revision; Romeo E and De Angelis P contributed to endoscopic treatment; Foschia F, Faraci S and Contini AC contributed to enrolling patients and data collecting; Caldaro T, Federici di Abriola G and Dall’Oglio L contributed to surgical treatment.
Supported by “Generazione e Sviluppo” Onlus, ASTALDI s.p.a. and Fondazione Charlemagne Onlus
Correspondence to: Filippo Torroni, MD, Department of Surgery and Transplantation, Digestive Surgery and Endoscopy Unit, Bambino Gesù Children’s Hospital, IRCCS, Piazza Sant’Onofrio 4, 00165 Rome, Italy. ftorroni@gmail.com
Telephone: +39-66-8592841 Fax: +39-66-8592949
Received: January 21, 2014
Revised: March 18, 2014
Accepted: June 20, 2014
Published online: July 16, 2014
Revised: March 18, 2014
Accepted: June 20, 2014
Published online: July 16, 2014
Core Tip
Core tip: Peutz-Jeghers syndrome (PJS) is an autosomal dominant disorder characterized by mucocutaneus pigmentation and multiple polyps in small bowel. Most of pts need surgical intervention for intussusceptions and gastrointestinal bleeding; the surgical risk is up to 50% in pts having a large polyps > 15 mm or rapidly growing. Enteroscopy balloon assisted with resection of small bowel large polyps is useful to avoid emergency laparotomy after performing wireless capsule endoscopy. The effective of prophylactic polypectomy of small bowel large polyps could be the first line treatment for conservative approach in management of PJS patients.