Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.
World J Gastrointest Endosc. Nov 16, 2026; 18(11): 126270
Published online Nov 16, 2026. doi: 10.4253/wjge.126270
Published online Nov 16, 2026. doi: 10.4253/wjge.126270
Endoscopic hemostatic powder spray: Current evidence and clinical applications
Wen-Wen Zhu, Xu-Lin Chen, Zhuo Yang, Ke Han, Wen Jia, Department of Endoscopy, General Hospital of Northern Theater Command, Shenyang 110016, Liaoning Province, China
Co-first authors: Wen-Wen Zhu and Xu-Lin Chen.
Author contributions: Zhu WW and Chen XL participated in the conception and design of the study and were involved in the acquisition, analysis, or interpretation of data; Zhu WW, Chen XL, and Jia W wrote the manuscript; Han K and Yang Z accessed and verified the study data; all authors critically reviewed and provided final approval of the manuscript; and all authors were responsible for the decision to submit the manuscript for publication.
AI contribution statement: The authors declare that no AI tools were used in the development or writing of this manuscript and take full responsibility for its integrity, accuracy, and originality.
Supported by Shenyang Science and Technology Plan, No. 22-321-32-15; National Natural Science Foundation of China, No. 82500816; Natural Science Foundation of Liaoning Province, No. 2025-BS-0946; and Liaoning Young Elite Scientists Sponsorship Program.
Conflict-of-interest statement: All authors declare that they have no conflict of interest to disclose.
Corresponding author: Zhuo Yang, PhD, Department of Endoscopy, General Hospital of Northern Theater Command, No. 83 Wenhua Road, Shenhe District, Shenyang 110016, Liaoning Province, China. yangzhuocy@163.com
Received: August 4, 2026
Revised: September 6, 2026
Accepted: October 16, 2026
Published online: November 16, 2026
Processing time: 106 Days and 17.8 Hours
Revised: September 6, 2026
Accepted: October 16, 2026
Published online: November 16, 2026
Processing time: 106 Days and 17.8 Hours
Core Tip
Core Tip: Hemostatic powder is an emerging endoscopic modality for gastrointestinal bleeding that enables rapid, technically simple hemostasis in difficult or anatomically complex bleeding sites. Given the uneven, largely observational evidence base, it is best positioned as a rescue, bridging, or adjunctive option in selected scenarios rather than routine first-line monotherapy. This minireview compares the mechanisms and clinical evidence of available powders and proposes a provisional recommendation.