Published online Aug 16, 2019. doi: 10.4253/wjge.v11.i8.454
Peer-review started: March 4, 2019
First decision: April 11, 2019
Revised: July 8, 2019
Accepted: July 20, 2019
Article in press: July 20, 2019
Published online: August 16, 2019
Core tip: Endoscopic ultrasound guided fine needle aspiration (FNA) is the gold standard for sampling solid pancreatic masses, but the small amount of tissue collected and the need of on site evaluation to maximize the diagnostic yield are some disadvantages. New fine needle biopsy (FNB) needles, with high safety profile and satisfying diagnostic accuracy even in absence of on site evaluation, could overcome FNA limitations. However, FNB has not yet shown a clear diagnostic superiority. Thus, in order to choose the better needle for a given scenario, it is important to know the technical aspects of FNA and FNB, the different sampling techniques, the types of needle available, and their diagnostic performance.